Evidence map›Paper›PMID 22654081›Full record

SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2012

What is the optimal management option for occupational asthma?

Olivier Vandenplas, Holger Dressel, Dennis Nowak, Jacques Jamart, ERS Task Force on the Management of Work-related Asthma

Abstract readSystematic Review
In one paragraph

Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Occupational Respiratory Allergy to Flour in the Modern Era.Current allergy and asthma reports · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Progress in Occupational Asthma.International journal of environmental research and public health · 2020
    Review
  8. Workplace interventions for treatment of occupational asthma.The Cochrane database of systematic reviews · 2019
    Review
  9. Asthma medication use among adults with current asthma by work-related asthma status, Asthma Call-back Survey, 29 states, 2012-2013.The Journal of asthma : official journal of the Association for the Care of Asthma · 2018
    Article
  10. Determinants of persistent asthma in young adults.European clinical respiratory journal · 2018
    Article
  11. Review of Diagnostic Challenges in Occupational Asthma.Current allergy and asthma reports · 2017
    Review
  12. Medical surveillance and long-term prognosis of occupational allergy due to platinum salts.International archives of occupational and environmental health · 2017
    Observational
  13. Article
  14. Laboratory Animal Allergy in the Modern Era.Current allergy and asthma reports · 2015
    Review
  15. Article
  16. Clinically relevant subgroups in COPD and asthma.European respiratory review : an official journal of the European Respiratory Society · 2015
    Review
  17. Specific inhalation challenge tests for occupational asthma in Europe: a survey.European respiratory review : an official journal of the European Respiratory Society · 2014
    Article
  18. Article
  19. Article
  20. Diagnostic approach in cases with suspected work-related asthma.Journal of occupational medicine and toxicology (London, England) · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olivier VandenplasDept of Chest Medicine, Mont-Godinne Hospital, Université Catholique De Louvain, Yvoir, Belgium. olivier.vandenplas@uclouvain.be
Holger Dressel
Dennis Nowak
Jacques Jamart
ERS Task Force on the Management of Work-related Asthma

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal management of occupational asthma remains uncertain in clinical practice. The aim of this review was to analyse the published information pertaining to the management of occupational asthma in order to produce evidence-based statements and recommendations. A systematic literature search was conducted up to March 2010 to identify original studies addressing the following different treatment options: 1) persistence of exposure; 2) pharmacological treatment; 3) complete avoidance of exposure; 4) reduction of exposure; and 5) the use of personal protective equipment. After full text evaluation of 83 potentially relevant articles, 52 studies were retained for analysis. The conclusions from this systematic review are limited by the methodological weaknesses of most published studies. Critical analysis of available evidence indicates that: 1) persistent exposure to the causal agent is more likely to result in asthma worsening than complete avoidance; 2) there is insufficient evidence to determine whether pharmacological treatment can alter the course of asthma in subjects who remain exposed; 3) avoidance of exposure leads to recovery of asthma in less than one-third of affected workers; 4) reduction of exposure seems to be less beneficial than complete avoidance of exposure; and 5) personal respiratory equipment does not provide complete protection.

Indexed as

Disease ManagementAnti-Asthmatic AgentsAsthma, OccupationalEvidence-Based MedicineHumansOccupational ExposureOutcome Assessment, Health CarePrognosisAnti-Asthmatic Agents

Identifiers

PMID22654081
PMCPMC9487291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.