ArticleEuropean radiology2012
Tumour size of resectable oesophageal squamous cell carcinoma measured with multidetector computed tomography for predicting regional lymph node metastasis and N stage.
Article in European radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- A novel pN stage prediction model for resectable rectal adenocarcinoma based on preoperative MRI features and multiregional apparent diffusion coefficients.European radiology · 2025Article
- Prediction of right recurrent laryngeal nerve lymph node metastasis in esophageal cancer based on computed tomography imaging histology.Frontiers in oncology · 2024Article
- CT radiomics in the identification of preoperative understaging in patients with clinical stage T1-2N0 esophageal squamous cell carcinoma.Quantitative imaging in medicine and surgery · 2023Article
- Article
- Clinical TNM staging for esophageal, gastric, and colorectal cancers in the era of neoadjuvant therapy: A systematic review of the literature.Annals of gastroenterological surgery · 2021Review
- Tumor size measured by multidetector CT in resectable colon cancer: correlation with regional lymph node metastasis and N stage.World journal of surgical oncology · 2021Article
- CT radiomics features to predict lymph node metastasis in advanced esophageal squamous cell carcinoma and to discriminate between regional and non-regional lymph node metastasis: a case control study.Quantitative imaging in medicine and surgery · 2021Article
- Value of Nomogram Incorporated Preoperative Tumor Volume and the Number of Postoperative Pathologically Lymph Node Metastasis Regions on Predicting the Prognosis of Thoracic Esophageal Squamous Cell Carcinoma.Cancer management and research · 2021Article
- The Predictive Value of Tumor Volume and Its Change on Short-Term Outcome for Esophageal Squamous Cell Carcinoma Treated With Radiotherapy or Chemoradiotherapy.Frontiers in oncology · 2020Article
- Volumetric analysis at abdominal CT: oncologic and non-oncologic applications.The British journal of radiology · 2019Review
- Tumour volume of resectable oesophageal squamous cell carcinoma measured with MRI correlates well with T category and lymphatic metastasis.European radiology · 2018Article
- Measurement of tumor volume is not superior to diameter for prediction of lymph node metastasis in early gastric cancer with minute submucosal invasion.Oncotarget · 2017Article
- Tumor volume of resectable gastric adenocarcinoma on multidetector computed tomography: association with N categories.Clinics (Sao Paulo, Brazil) · 2016Article
- Primary Gross Tumor Volume is an Important Prognostic Factor in Locally Advanced Esophageal Cancer Patients Treated with Trimodality Therapy.Journal of gastrointestinal cancer · 2015Article
- Computed tomography versus magnetic resonance imaging for diagnosing cervical lymph node metastasis of head and neck cancer: a systematic review and meta-analysis.OncoTargets and therapy · 2015Review
- Extraesophageal saline enhances endoscopic ultrasonography to differentiate esophagus and adjacent organs.World journal of gastroenterology · 2014Article
- Diagnostic accuracy of diffusion-weighted magnetic resonance imaging for cervical lymph node metastasis from oral cancer.Radiologia brasileiraArticle
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Authors and funding
10 authors.
Funding
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Abstract
objectivesTo determine whether and how tumour size of resectable oesophageal squamous cell carcinoma (ESCC) measured with multidetector CT could predict regional lymph node metastasis (LNM) and N stage.
methodsTwo hundred five patients with ESCC underwent radical oesophagectomy with three-field lymphadenectomy less than 3 weeks after contrast-enhanced CT. Tumour size of the ESCC (tumour length, maximal thickness and gross tumour volume, GTV) was measured on CT. Statistical analyses were performed to identify whether tumour size could predict regional LNM and N stage, and to determine how to use the size of ESCC to predict N stage.
resultsUnivariate analysis showed that tumour size could predict regional LNM (all P < 0.05). Logistic regression analysis revealed that GTV could independently predict regional LNM (P = 0.021, odds ratio = 1.813). Mann-Whitney tests showed that tumour size could distinguish grouped N stages (all P < 0.05). GTV might be a differentiating indicator between N0 and N1-3 stages (cutoff, 14.4 cm(3)), between N0-1 and N2-3 (cutoff, 15.9 cm(3)), and between N0-2 and N3 (cutoff, 26.1 cm(3)), with sensitivity of 76%, 63% or 75%, and specificity of 75%, 61% and 81%, respectively.
conclusionsThe GTV of ESCC measured with CT could be an indicator for predicting regional LNM and grouped N stages. KEY POINTS : • Multidetector computed tomography (MDCT) allows accurate assessment of oesophageal tumour size • For resectable squamous cell tumours, size helped predict regional lymph node involvement • Gross tumour volume may predict the N stage of oesophageal squamous cell carcinoma.
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