ReviewThe Israel journal of psychiatry and related sciences2012
Prevalence, clinical presentation and differential diagnosis of pediatric bipolar disorder.
Review in The Israel journal of psychiatry and related sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Ketamine for mood disorders, anxiety, and suicidality in children and adolescents: a systematic review.European child & adolescent psychiatry · 2025Pooled it
- Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder.Bipolar disorders · 2018Guideline
- Data Diversity vs. Model Complexity in the Prediction of Pediatric Bipolar Disorder: Evidence from Academic and Community Clinical Samples.medRxiv : the preprint server for health sciences · 2026Article
- Comparing Youth With Bipolar Disorder to Non-Bipolar Youth Referred for Bipolar Disorder.JAACAP open · 2025Article
- Childhood Clinical Features Preceding the Onset of Bipolar Versus Major Depressive Disorders During Adolescence.Journal of attention disorders · 2024Article
- Comorbidity in pediatric bipolar disorder: An unmet challenge in need of treatment studies.Acta psychiatrica Scandinavica · 2023Article
- Cell-type-specific genes associated with cortical structural abnormalities in pediatric bipolar disorder.Psychoradiology · 2022Article
- Shared and specific patterns of structural and functional thalamo-frontal disturbances in manic and euthymic pediatric bipolar disorder.Brain imaging and behavior · 2021Article
- Altered neurochemistry in the anterior white matter of bipolar children and adolescents: a multivoxelMolecular psychiatry · 2021Article
- Not Only Mania or Depression: Mixed States/Mixed Features in Paediatric Bipolar Disorders.Brain sciences · 2021Review
- Neonatal Negative Emotionality and the Child Behavior Checklist-Dysregulation Profile (CBCL-DP) in middle childhood.Journal of reproductive and infant psychology · 2021Article
- Comorbidity and patterns of familial aggregation in attention-deficit/hyperactivity disorder and bipolar disorder in a family study of affective and anxiety spectrum disorders.Journal of psychiatric research · 2020Article
- Disrupted brain structural connectivity in Pediatric Bipolar Disorder with psychosis.Scientific reports · 2019Article
- Treatment patterns of youth with bipolar disorder: results from the National Comorbidity Survey-Adolescent Supplement (NCS-A).Journal of abnormal child psychology · 2015Article
- Re-examining the risk for switch from unipolar to bipolar major depressive disorder in youth with ADHD: a long term prospective longitudinal controlled study.Journal of affective disorders · 2014Article
- Anxiety disorders and rapid cycling: data from a cohort of 8129 youths with bipolar disorder.The Journal of nervous and mental disease · 2013Article
- A Case of Neurological Symptoms and Severe Urinary Retention on a Pediatric Ward: Is this Conversion Disorder?Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundOver the past 20 years, the evidence regarding pediatric bipolar disorder (BP) has increased substantially. As a result, recent concerns have focused primarily on prevalence and differential diagnosis.
methodSelective review of the literature.
resultsBP as defined by rigorously applying diagnostic criteria has been observed among children and especially adolescents in numerous countries. In contrast to increasing diagnoses in clinical settings, prevalence in epidemiologic studies has not recently changed. BPspectrum conditions among youth are highly impairing and confer high risk for conversion to BP-I and BP-II. Compared to adults, youth with BP have more mixed symptoms, more changes in mood polarity, are more often symptomatic and seem to have worse prognosis. The course, clinical characteristics, and comorbidities of BP among children and adolescents are in many ways otherwise similar to those of adults with BP. Nonetheless, many youth with BP receive no treatment and most do not receive BP-specific treatment.
conclusionDespite increased evidence supporting the validity of pediatric BP, discrepancies between clinical and epidemiologic findings suggest that diagnostic misapplication may be common. Simultaneously, low rates of treatment of youth with BP suggest that withholding of BP diagnoses may also be common. Clinicians should apply diagnostic criteria rigorously in order to optimize diagnostic accuracy and ensure appropriate treatment.
Indexed as
Identifiers
22652925PMC5027964W2404764644What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.