ReviewFrontiers in bioscience (Scholar edition)2012
Autophagy: mechanism and physiological relevance 'brewed' from yeast studies.
Review in Frontiers in bioscience (Scholar edition), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- APOE4 impairs autophagy and Aβ clearance by microglial cells.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Article
- The synergistic mechanisms of propofol with cisplatin or doxorubicin in human ovarian cancer cells.Journal of ovarian research · 2024Article
- The Role of Autophagy and Apoptosis in Affected Skin and Lungs in Patients with Systemic Sclerosis.International journal of molecular sciences · 2023Review
- Apoptosis, Proliferation, and Autophagy Are Involved in Local Anesthetic-Induced Cytotoxicity of Human Breast Cancer Cells.International journal of molecular sciences · 2022Article
- Senescence and autophagy in usual interstitial pneumonia of different etiology.Virchows Archiv : an international journal of pathology · 2021Article
- Autophagy and cardiac aging.Cell death and differentiation · 2019Review
- Review
- Roles of endoplasmic reticulum stress and autophagy on H2O2‑induced oxidative stress injury in HepG2 cells.Molecular medicine reports · 2018Article
- Article
- Transcriptional variations in the wider peritumoral tissue environment of pancreatic cancer.International journal of cancer · 2018Article
- The Malleable Nature of the Budding Yeast Nuclear Envelope: Flares, Fusion, and Fenestrations.Journal of cellular physiology · 2016Review
- An overview of macroautophagy in yeast.Journal of molecular biology · 2016Review
- ER stress: Autophagy induction, inhibition and selection.Autophagy · 2015Article
- Article
- Reserve autophagic capacity in alveolar epithelia provides a replicative niche for influenza A virus.American journal of respiratory cell and molecular biology · 2014Article
- An overview of autophagy: morphology, mechanism, and regulation.Antioxidants & redox signaling · 2014Review
- Binding to E1 and E3 is mutually exclusive for the human autophagy E2 Atg3.Protein science : a publication of the Protein Society · 2013Article
- Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast.Experimental gerontology · 2013Article
- Spg5 protein regulates the proteasome in quiescence.The Journal of biological chemistry · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Autophagy is a highly conserved process of quality control occurring inside cells by which cytoplasmic material can be degraded and the products recycled for use as new building blocks or for energy production. The rapid progress and 'explosion' of knowledge concerning autophagic processes in mammals/humans that has occurred over the last 15 years was driven by fundamental studies in yeast, principally using Saccharomyces cerevisiae, leading to the identification and cloning of genes required for autophagy. This chapter reviews the role of yeast studies in understanding the molecular mechanisms of autophagic processes, focusing on aspects that are conserved in mammals/humans and how autophagy is increasingly implicated in the pathogenesis of disease and is required for development and differentiation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.