ArticleNeurotoxicology and teratology2012
Memory ability and hippocampal volume in adolescents with prenatal drug exposure.
Article in Neurotoxicology and teratology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Pooled it
- The Earliest Impressions: A Systematic Review of Early-Life Exposures on Brain Structure and Neurodevelopmental Outcomes.bioRxiv : the preprint server for biology · 2026Article
- Do spatial navigation and episodic memory rely on the same systems? Evidence from a naturalistic experience with children and adults.Journal of experimental psychology. General · 2025Article
- Hippocampal and amygdala volumes vary with residential proximity to toxicants at Birmingham, Alabama's 35th Avenue Superfund site.Behavioral neuroscience · 2023Article
- Prenatal heroin exposure alters brain morphology and connectivity in adolescent mice.NMR in biomedicine · 2023Article
- Early emotional caregiving environment and associations with memory performance and hippocampal volume in adolescents with prenatal drug exposure.Frontiers in behavioral neuroscience · 2023Article
- Brain structural connectome in neonates with prenatal opioid exposure.Frontiers in neuroscience · 2022Article
- Neuroimaging in infants with prenatal opioid exposure: Current evidence, recent developments and targets for future research.Journal of neuroradiology = Journal de neuroradiologie · 2021Review
- Prenatal Drug Exposure and Adolescent Cortisol Reactivity: Association with Behavioral Concerns.Journal of developmental and behavioral pediatrics : JDBP · 2016Article
- Pioneers in pediatric psychology: integrating nutrition and child development interventions.Journal of pediatric psychology · 2015Article
- Relations among prospective memory, cognitive abilities, and brain structure in adolescents who vary in prenatal drug exposure.Journal of experimental child psychology · 2014Article
- Longitudinal growth and morphology of the hippocampus through childhood: Impact of prematurity and implications for memory and learning.Human brain mapping · 2014Article
- Hippocampal Volume in Type 1 Diabetes.European endocrinology · 2014Review
- Prenatal drug exposure moderates the association between stress reactivity and cognitive function in adolescence.Developmental neuroscience · 2014Article
- Level of intrauterine cocaine exposure and neuropsychological test scores in preadolescence: subtle effects on auditory attention and narrative memory.Neurotoxicology and teratologyArticle
- Prenatal drug exposure to illicit drugs alters working memory-related brain activity and underlying network properties in adolescence.Neurotoxicology and teratologyArticle
- Long-term effects of prenatal drug exposure on the neural correlates of memory at encoding and retrieval.Neurotoxicology and teratologyArticle
- Early-life manganese exposure during multiple developmental periods and adolescent verbal learning and memory.Neurotoxicology and teratologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
The objective of the present study was to examine the influence of prenatal drug exposure (PDE) on memory performance and supporting brain structures (i.e., hippocampus) during adolescence. To achieve this goal, declarative memory ability and hippocampal volume were examined in a well-characterized sample of 138 adolescents (76 with a history of PDE and 62 from a non-exposed comparison group recruited from the same community, mean age=14 years). Analyses were adjusted for: age at time of the assessments, gender, IQ, prenatal exposure to alcohol and tobacco, and indices of early childhood environment (i.e., caregiver depression, potential for child abuse, and number of caregiver changes through 7 years of age). Results revealed that adolescents with a history of PDE performed worse on the California Verbal Learning Test-Child Version (CVLT-C), and story recall from the Children's Memory Scale (CMS), and had larger hippocampal volumes, even after covariate adjustment. Hippocampal volume was negatively correlated with memory performance on the CVLT-C, with lower memory scores associated with larger volumes. These findings provide support for long-term effects of PDE on memory function and point to neural mechanisms that may underlie these outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.