ReviewTrends in biotechnology2012
Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology.
Review in Trends in biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Digital Phenotyping for Stress, Anxiety, and Mild Depression: Systematic Literature Review.JMIR mHealth and uHealth · 2024Pooled it
- Zebrafish swimming towards cures: a scalable NAM platform for drug discovery.Drug discovery today · 2026Review
- Article
- Knockout ofInternational journal of molecular sciences · 2022Article
- Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles.Scientific reports · 2022Article
- Phenotype-Based HPLC-Q-TOF-MS/MS Coupled With Zebrafish Behavior Trajectory Analysis System for the Identification of the Antidepressant Components in Methanol Extract of Anshen Buxin Six Pills.Frontiers in pharmacology · 2021Article
- The zebrafish subcortical social brain as a model for studying social behavior disorders.Disease models & mechanisms · 2019Review
- Towards High-Throughput Chemobehavioural Phenomics in Neuropsychiatric Drug Discovery.Marine drugs · 2019Review
- Impact of digital video analytics on accuracy of chemobehavioural phenotyping in aquatic toxicology.PeerJ · 2019Article
- High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy.Science advances · 2018Article
- LITTLE FISH, BIG DATA: ZEBRAFISH AS A MODEL FOR CARDIOVASCULAR AND METABOLIC DISEASE.Physiological reviews · 2017Review
- Animated images in the analysis of zebrafish behavior.Current zoology · 2017Article
- Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds.Nature chemical biology · 2016Article
- Leveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology.ACS chemical biology · 2016Article
- 15 years of zebrafish chemical screening.Current opinion in chemical biology · 2015Article
- FutureTox II: in vitro data and in silico models for predictive toxicology.Toxicological sciences : an official journal of the Society of Toxicology · 2015Article
- Developing highER-throughput zebrafish screens for in-vivo CNS drug discovery.Frontiers in behavioral neuroscience · 2015Article
- Article
- Combining motion analysis and microfluidics--a novel approach for detecting whole-animal responses to test substances.PloS one · 2014Article
- Larval zebrafish model for FDA-approved drug repositioning for tobacco dependence treatment.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
For decades, studying the behavioral effects of individual drugs and genetic mutations has been at the heart of efforts to understand and treat nervous system disorders. High-throughput technologies adapted from other disciplines (e.g., high-throughput chemical screening, genomics) are changing the scale of data acquisition in behavioral neuroscience. Massive behavioral datasets are beginning to emerge, particularly from zebrafish labs, where behavioral assays can be performed rapidly and reproducibly in 96-well, high-throughput format. Mining these datasets and making comparisons across different assays are major challenges for the field. Here, we review behavioral barcoding, a process by which complex behavioral assays are reduced to a string of numeric features, facilitating analysis and comparison within and across datasets.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.