ArticleInterface focus2012
The effect of the signalling scheme on the robustness of pattern formation in development.
Article in Interface focus, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Patterning, From Conifers to Consciousness: Turing's Theory and Order From Fluctuations.Frontiers in cell and developmental biology · 2022Review
- Size matters: tissue size as a marker for a transition between reaction-diffusion regimes in spatio-temporal distribution of morphogens.Royal Society open science · 2022Article
- Improving the understanding of cytoneme-mediated morphogen gradients by in silico modeling.PLoS computational biology · 2021Article
- Multiscale Stochastic Reaction-Diffusion Algorithms Combining Markov Chain Models with Stochastic Partial Differential Equations.Bulletin of mathematical biology · 2019Article
- Single-cell resolution of intracellular T cell CaIntegrative biology : quantitative biosciences from nano to macro · 2017Article
- Local homeoprotein diffusion can stabilize boundaries generated by graded positional cues.Development (Cambridge, England) · 2015Article
- The role of mathematical models in understanding pattern formation in developmental biology.Bulletin of mathematical biology · 2015Article
- Stochastic analysis of reaction-diffusion processes.Bulletin of mathematical biology · 2014Article
- Mechanisms of scaling in pattern formation.Development (Cambridge, England) · 2013Review
- External noise control in inherently stochastic biological systems.Journal of mathematical physics · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Pattern formation in development is a complex process which involves spatially distributed signals called morphogens that influence gene expression and thus the phenotypic identity of cells. Usually different cell types are spatially segregated, and the boundary between them may be determined by a threshold value of some state variable. The question arises as to how sensitive the location of such a boundary is to variations in properties, such as parameter values, that characterize the system. Here, we analyse both deterministic and stochastic reaction-diffusion models of pattern formation with a view towards understanding how the signalling scheme used for patterning affects the variability of boundary determination between cell types in a developing tissue.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.