ArticleFrontiers in endocrinology2011
Cross-Talk between Metabolism and Reproduction: The Role of POMC and SF1 Neurons.
Article in Frontiers in endocrinology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Melanocortin 4 receptor signaling in Sim1 neurons permits sexual receptivity in female mice.Frontiers in endocrinology · 2023Article
- Exogenous Melatonin Regulates Puberty and the Hypothalamic GnRH-GnIH System in Female Mice.Brain sciences · 2022Article
- Possible Role of GnIH as a Novel Link between Hyperphagia-Induced Obesity-Related Metabolic Derangements and Hypogonadism in Male Mice.International journal of molecular sciences · 2022Article
- Early Postnatal Genistein Administration Affects Mice Metabolism and Reproduction in a Sexually Dimorphic Way.Metabolites · 2021Article
- Photoperiodically driven transcriptome-wide changes in the hypothalamus reveal transcriptional differences between physiologically contrasting seasonal life-history states in migratory songbirds.Scientific reports · 2021Article
- A cross-talk between leptin and 17β-estradiol in vitellogenin synthesis in rainbow trout Oncorhynchus mykiss liver.Fish physiology and biochemistry · 2020Article
- Article
- Metabolism Disrupting Chemicals and Alteration of Neuroendocrine Circuits Controlling Food Intake and Energy Metabolism.Frontiers in endocrinology · 2018Review
- Melanocortin 4 receptor is not required for estrogenic regulations on energy homeostasis and reproduction.Metabolism: clinical and experimental · 2017Article
- Liver ERα regulates AgRP neuronal activity in the arcuate nucleus of female mice.Scientific reports · 2017Article
- Defining a novel leptin-melanocortin-kisspeptin pathway involved in the metabolic control of puberty.Molecular metabolism · 2016Article
- Neuroinflammatory and autonomic mechanisms in diabetes and hypertension.American journal of physiology. Endocrinology and metabolism · 2016Review
- Lactation undernutrition leads to multigenerational molecular programming of hypothalamic gene networks controlling reproduction.BMC genomics · 2016Article
- Deferred feeding and body weight responses to short-term interruption of fuel acquisition: impact of estradiol.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2015Article
- Fertility-regulating Kiss1 neurons arise from hypothalamic POMC-expressing progenitors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- From precocious puberty to infertility: metabolic control of the reproductive function.Frontiers in endocrinology · 2013Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Energy homeostasis and reproduction require tight coordination, but the mechanisms underlying their interaction are not fully understood. Two sets of hypothalamic neurons, namely pro-opiomelanocortin (POMC) neurons in the arcuate nucleus and steroidogenic factor-1 (SF1) neurons in the ventromedial hypothalamic nucleus, are emerging as critical nodes where metabolic and reproductive signals communicate. This view is supported by recent genetic studies showing that disruption of metabolic signals (e.g., leptin and insulin) or reproductive signals (e.g., estradiol) in these neurons leads to impaired regulation of both energy homeostasis and fertility. In this review, we will examine the potential mechanisms of neuronal communication between POMC, SF1, and gonadotropin-releasing hormone neurons in the regulation of metabolism and reproduction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.