Evidence map›Paper›PMID 22649342›Full record

ArticleCase reports in neurology2012

A case of relapsing-remitting neuroborreliosis? Challenges in the differential diagnosis of recurrent myelitis.

P Albrecht, N Henke, H C Lehmann, S Macht, H Hefter, N Goebels, C Mackenzie, T A Rupprecht, V Fingerle, H P Hartung and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

P AlbrechtDepartment of Neurology, Heinrich Heine University, Düsseldorf, Oberschleissheim, Germany.
N Henke
H C Lehmann
S Macht
H Hefter
N Goebels
C Mackenzie
T A Rupprecht
V Fingerle
H P Hartung
A Methner
Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit · DEHeinrich Heine University Düsseldorf · DEHelios Amper-Klinikum Dachau · DESociety of Interventional Radiology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 31-year-old woman with 4 episodes of myelitis with pleocytosis, a positive Borrelia burgdorferi serology with positive antibody indices, and full recovery each time after antibiotic and steroid treatment, suggesting neuroborreliosis. We nevertheless believe that recurrent neuroborreliosis is improbable based on the levels of the chemokine CXCL13 in cerebrospinal fluid and favor the diagnosis of post-infectious autoimmune-mediated transverse myelitis possibly triggered by an initial neuroborreliosis as the cause of the relapses observed in our patient. We demonstrate the diagnostic steps and procedures which were important in the differential diagnosis of this unusual and challenging case.

Indexed as

Borrelia burgdorferiCerebrospinal fluidCXCL13Lyme borreliosisMyelitisNeuroborreliosis

Identifiers

PMID22649342
PMCPMC3362302
OpenAlexW1980803585

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.