Evidence map›Paper›PMID 22649222›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012

The diffusion tensor imaging toolbox.

Jeffry R Alger

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Effects of simvastatin on white matter integrity in healthy middle-aged adults.Annals of clinical and translational neurology · 2021
    Trial
  3. Article
  4. Article
  5. Review
  6. Interaction of amyloid and tau on cortical microstructure in cognitively unimpaired adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Phantom-based field maps for gradient nonlinearity correction in diffusion imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jeffry R AlgerDepartment of Neurology, Department of Radiological Sciences, Interdepartmental Program in Biomedical Engineering, Ahmanson-Lovelace Brain Mapping Center, Brain Research Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-7085, USA. jralger@ucla.edu

Funding

UCLA SPOTRIAS CENTER APPLICATION RENEWAL-PROGRAM PROJECTP50NS044378 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SAVER, JEFFREY L · 2003 to 2012
$17.2M
PARTNERSHIP FOR MR SPECTROSCOPIC IMAGING DATA PROCESSINGR01EB000822 · NIBIB · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MAUDSLEY, ANDREW A. · 2002 to 2012
$10.8M
Neurobiological endophenotypes & gene-environment interactions in IC/PBS & in aU01DK082370 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KUTCH, JASON J., MAYER, EMERAN A · 2008 to 2021
$9.2M
Cognitive-Behavioral Therapy & Glutametergic Neurometabolites in Pediatric OCDR01MH081864 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI O'NEILL, JOSEPH, PIACENTINI, JOHN C. · 2008 to 2012
$3.0M
Reconnection of Neural Networks and Cognitive Recovery after Pediatric TBIR01HD061504 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ASARNOW, ROBERT F · 2010 to 2014
$2.9M
Neuroimaging and Neurochemical Biomarkers in ADHDRC1MH088507 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEVITT, JENNIFER G., LOO, SANDRA K · 2009 to 2010
$999k
Mechanisms Altering Electrical Conductivity & DTI in Epilepsy Surgery PatientsR21NS060675 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MATHERN, GARY W. · 2010 to 2011
$420k
NIBIB NIH HHS EB00822NIBIB NIH HHS R01 EB000822NICHD NIH HHS R01 HD061504NIDDK NIH HHS DK082370NIDDK NIH HHS U01 DK082370NIMH NIH HHS MH081864NIMH NIH HHS MH088507NIMH NIH HHS R01 MH081864NIMH NIH HHS RC1 MH088507NINDS NIH HHS NS044378NINDS NIH HHS NS060675NINDS NIH HHS P50 NS044378NINDS NIH HHS R21 NS060675
6 · The paper itself

Abstract

During the past few years, The Journal of Neuroscience has published more than 30 articles that describe investigations that used Diffusion Tensor Imaging (DTI) and related techniques as a primary observation method. This illustrates a growing interest in DTI within the basic and clinical neuroscience communities. This article summarizes DTI methodology in terms that can be immediately understood by the neuroscientist who has little previous exposure to DTI. It describes the fundamentals of water molecular diffusion coefficient measurement in brain tissue and illustrates how these fundamentals can be used to form vivid and useful depictions of white matter macroscopic and microscopic anatomy. It also describes current research applications and the technique's attributes and limitations. It is hoped that this article will help the readers of this Journal to more effectively evaluate neuroscience studies that use DTI.

Indexed as

Diffusion Tensor ImagingAnimalsAnisotropyBrainBrain MappingDiffusionHumansImage Processing, Computer-AssistedNerve Fibers, MyelinatedNeural PathwaysWaterWater

Identifiers

PMID22649222
PMCPMC3444512

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.