ArticleJournal of biophotonics2013
Multimodal photoacoustic ophthalmoscopy in mouse.
Article in Journal of biophotonics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Advanced nanomaterials for imaging of eye diseases.ADMET & DMPK · 2024Review
- Retinal safety evaluation of photoacoustic microscopy.Experimental eye research · 2021Article
- High Resolution Multimodal Photoacoustic Microscopy and Optical Coherence Tomography Visualization of Choroidal Vascular Occlusion.International journal of molecular sciences · 2020Article
- Advances in Retinal Optical Imaging.Photonics · 2018Article
- Large area laser scanning optical resolution photoacoustic microscopy using a fibre optic sensor.Biomedical optics express · 2018Article
- Imaging retinal melanin: a review of current technologies.Journal of biological engineering · 2018Review
- Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development.Investigative ophthalmology & visual science · 2017Article
- Increased Retinal Oxygen Metabolism Precedes Microvascular Alterations in Type 1 Diabetic Mice.Investigative ophthalmology & visual science · 2017Article
- Photoacoustic imaging features of intraocular tumors: Retinoblastoma and uveal melanoma.PloS one · 2017Article
- Photoacoustic imaging of the eye: A mini review.Photoacoustics · 2016Review
- Tutorial on photoacoustic tomography.Journal of biomedical optics · 2016Review
- Simultaneous optical coherence tomography angiography and fluorescein angiography in rodents with normal retina and laser-induced choroidal neovascularization.Optics letters · 2015Article
- A combined method to quantify the retinal metabolic rate of oxygen using photoacoustic ophthalmoscopy and optical coherence tomography.Scientific reports · 2014Article
- Light in and sound out: emerging translational strategies for photoacoustic imaging.Cancer research · 2014Review
- Accuracy of retinal oximetry: a Monte Carlo investigation.Journal of biomedical optics · 2013Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Photoacoustic ophthalmoscopy (PAOM) is a novel imaging technology that measures optical absorption in the retina. The capability of PAOM can be further enhanced if it could image mouse eyes, because mouse models are widely used for various retinal diseases. The challenges in achieving high-quality imaging of mouse retina, however, come from the much smaller eyeball size. Here, we report an optimized imaging system, which integrates PAOM, spectral-domain optical coherence tomography (SD-OCT), and autofluorescence-scanning laser ophthalmoscopy (AF-SLO), for mouse eyes. Its multimodal capability was demonstrated by imaging transgenic Nrl-GFP mice that express green fluorescent protein (GFP) in photoreceptors. SD-OCT provided guidance of optical alignment for PAOM and AF-SLO, and complementary contrast with high depth-resolution retinal cross sections. PAOM visualized the retinal vasculature and retinal pigment epithelium melanin, and AF-SLO measured GFP-expressing in retinal photoreceptors. The in vivo imaging results were verified by histology and confocal microscopy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.