Evidence map›Paper›PMID 22648727›Full record

ArticleThe American journal of clinical nutrition2012

Vitamin D intake is inversely related to risk of developing metabolic syndrome in African American and white men and women over 20 y: the Coronary Artery Risk Development in Young Adults study.

Grace J Fung, Lyn M Steffen, Xia Zhou, Lisa Harnack, Weihong Tang, Pamela L Lutsey, Catherine M Loria, Jared P Reis, Linda V Van Horn

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in The American journal of clinical nutrition, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Grace J FungDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454, USA.
Lyn M Steffen
Xia Zhou
Lisa Harnack
Weihong Tang
Pamela L Lutsey
Catherine M Loria
Jared P Reis
Linda V Van Horn
National Institutes of Health · USNorthwestern University · USUniversity of Minnesota · US

Funding

CORONARY ARTERY DISEASE RISK DEVELOPMENT IN YOUNG ADULTS-N01HC95095-268095095N01HC095095 · HC · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILLIAMS, DALE · 1989 to 2006
$376k
CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048047 · HC · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E · 1985 to 2000
$171k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048050 · HC · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 1985 to 2000
$102k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048049 · HC · NORTHWESTERN UNIVERSITY · PI LIU, KIANG JOHN · 1985 to 2000
$71k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048048 · HC · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SCHREINER, PAMELA J · 1985 to 2000
$53k
CARDIA-ECHOCARDIOGRAPHY READINGN01HC045134 · HC · UNIVERSITY OF CALIFORNIA IRVINE · PI GARDIN, JULIUS M · 1994 to 2000
–
NHLBI NIH HHS N01-HC-45134NHLBI NIH HHS N01-HC-48047NHLBI NIH HHS N01-HC-48048NHLBI NIH HHS N01-HC-48049NHLBI NIH HHS N01-HC-48050NHLBI NIH HHS N01-HC-95095
6 · The paper itself

Abstract

backgroundVitamin D intake may play a key role in the prevention of cardiovascular disease.

objectiveWe evaluated associations of dietary and supplemental vitamin D intake with the 20-y incidence of metabolic syndrome.

designData from 4727 black and white young men and women from the Coronary Artery Risk Development in Young Adults study were used to examine relations of dietary plus supplemental vitamin D intake with the incidence of metabolic syndrome (as defined by Adult Treatment Panel, third report, guidelines) and the prevalence of its components, including abdominal obesity, elevated blood pressure, and high glucose, low HDL, and high triglyceride concentrations.

resultsThe intake of vitamin D from dietary and supplemental sources was inversely related to the 20-y cumulative prevalence of abdominal obesity (P = 0.05) and high glucose (P = 0.02) and low HDL (P = 0.004) concentrations after adjustment for age, sex, race, education, center, and energy intake. In comparison with the lowest intake quintile (quintile 1), HRs (95% CIs) of developing incident metabolic syndrome for quintiles 2-5 of vitamin D intake were 0.82 (0.67, 1.00), 0.84 (0.68, 1.03), 0.70 (0.56, 0.88), and 0.82 (95% CI: 0.65, 1.02), respectively (P-trend = 0.03) after adjustment for demographic and lifestyle factors.

conclusionsIn young adults, the dietary plus supplemental vitamin D intake was inversely related to the development of incident metabolic syndrome over 20 y of follow-up. These findings support the recommendations of the Dietary Guidelines for Americans to increase intakes of vitamin D-rich foods, such as milk and fish.

Indexed as

Black or African AmericanDietDietary SupplementsWhite People25-Hydroxyvitamin D 2AdultCalcifediolFemaleHumansHyperglycemiaIncidenceLongitudinal StudiesMaleMetabolic SyndromeObesity, AbdominalPrevalence25-Hydroxyvitamin D 2CalcifediolVitamin D

Identifiers

PMID22648727
PMCPMC3374731
OpenAlexW2127459259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.