Evidence map›Paper›PMID 22648574›Full record

ArticleAnnals of biomedical engineering2012

Trabecular level analysis of bone cement augmentation: a comparative experimental and finite element study.

Y Zhao, K A Robson Brown, Z M Jin, R K Wilcox

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Annals of biomedical engineering, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Peri-implant stress correlates with bone and cement morphology: Micro-FE modeling of implanted cadaveric glenoids.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2015
    Article
  6. Characterisation of a metallic foam-cement composite under selected loading conditions.Journal of materials science. Materials in medicine · 2013
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Y ZhaoInstitute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, UK.
K A Robson Brown
Z M Jin
R K Wilcox
University of Leeds · GBUniversity of Bristol · GB

Funding

Wellcome TrustWellcome Trust WT 088908/Z/09/Z
6 · The paper itself

Abstract

The representation of cement-augmented bone in finite element (FE) models of vertebrae following vertebroplasty remains a challenge, and the methods of the model validation are limited. The aim of this study was to create specimen-specific FE models of cement-augmented synthetic bone at the microscopic level, and to develop a new methodology to validate these models. An open cell polyurethane foam was used reduce drying effects and because of its similar structure to osteoporotic trabecular bone. Cylindrical specimens of the foam were augmented with PMMA cement. Each specimen was loaded to three levels of compression inside a micro-computed tomography (μCT) scanner and imaged both before compression and in each of the loaded states. Micro-FE models were generated from the unloaded μCT images and displacements applied to match measurements taken from the images. A morphological comparison between the FE-predicted trabecular deformations and the corresponding experimental measurements was developed to validate the accuracy of the FE model. The predicted deformation was found to be accurate (less than 12% error) in the elastic region. This method can now be used to evaluate real bone and different types of bone cements for different clinical situations.

Indexed as

ElasticityFinite Element AnalysisModels, BiologicalOsteoporosisBone and BonesBone CementsCompressive StrengthHumansX-Ray MicrotomographyBone Cements

Identifiers

PMID22648574
PMCPMC3438401
OpenAlexW1993107081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.