Evidence map›Paper›PMID 22648514›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2012

⁸²Rb PET myocardial perfusion imaging is superior to ⁹⁹mTc-labelled agent SPECT in patients with known or suspected coronary artery disease.

Albert Flotats, Paco E Bravo, Kenji Fukushima, Muhammad A Chaudhry, Jennifer Merrill, Frank M Bengel

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Article in European journal of nuclear medicine and molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Review
  3. Quantitative myocardial perfusionJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  4. Development, diagnostic performance, and interobserver agreement of aJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  5. Article
  6. Review
  7. Lost in quantification…: The influence of different software packages on flow quantification measures.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  8. The effect of time-of-flight and point spread function modeling onJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  9. Left ventricular function in response to dipyridamole stress: head-to-head comparison betweenEuropean journal of nuclear medicine and molecular imaging · 2017
    Article
  10. Cardiac Applications of PET-MR.Current cardiology reports · 2017
    Review
  11. SPECT myocardial blood flow quantitation toward clinical use: a comparative study withEuropean journal of nuclear medicine and molecular imaging · 2017
    Article
  12. Review
  13. The value and appropriateness of positron emission tomography: an evolving tale.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  14. Review
  15. Impact of point spread function modeling and time-of-flight on myocardial blood flow and myocardial flow reserve measurements for rubidium-82 cardiac PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Article
  16. Article
  17. Crown years for non-invasive cardiovascular imaging (Part II): 40 years of nuclear cardiology.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2013
    Article
  18. PET and SPECT in heart failure.Current cardiology reports · 2013
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Albert FlotatsDivision of Nuclear Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA. aflotats@santpau.cat
Paco E Bravo
Kenji Fukushima
Muhammad A Chaudhry
Jennifer Merrill
Frank M Bengel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe compared the quality, interpretive confidence and interreader agreement between SPECT and PET myocardial perfusion imaging (MPI) in the same group of patients.

methodsThe study group comprised 27 patients (age 55 ± 8.5 years, 12 men) with known or suspected coronary artery disease (CAD) who had undergone gated rest/stress MPI with (99m)Tc-labelled agent SPECT (with and without attenuation correction, AC), and subsequent clinical confirmation with (82)Rb PET. Three experienced readers blinded to the clinical information interpreted all MPI studies.

resultsInterreader agreement was significantly superior for PET studies than for SPECT studies. Following consensus interpretation, the quality of 22 % of the non-AC SPECT studies, 33 % of the AC SPECT studies and 63 % of the PET studies was assessed as excellent or good (p = 0.016). Interpretations were definitely normal or abnormal in 7 % of non-AC SPECT studies, 30 % of AC SPECT studies and 85 % of PET studies (p = 0.046). In 13 patients who had received either invasive coronary angiography or CT angiography with no significant CAD, the true-positive rate for significant CAD was higher for PET, and the true-negative rate was equal for PET and AC SPECT, and lower for non-AC SPECT.

conclusion(82)Rb PET MPI, used as a confirmatory test after SPECT, offers improved image quality, interpretive confidence and interreader agreement.

Indexed as

Organotechnetium CompoundsRubidium RadioisotopesAdultCoronary Artery DiseaseFemaleHumansImage Interpretation, Computer-AssistedIsotope LabelingMaleMiddle AgedMyocardial Perfusion ImagingPositron-Emission TomographyTomography, Emission-Computed, Single-PhotonOrganotechnetium CompoundsRubidium Radioisotopes

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.