ReviewJournal of neurology2012
CCSVI and MS: a statement from the European Society of neurosonology and cerebral hemodynamics.
Review in Journal of neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- Multimodal noninvasive and invasive imaging of extracranial venous abnormalities indicative of CCSVI: results of the PREMiSe pilot study.BMC neurology · 2013Trial
- Centralized and Local Color Doppler Ultrasound Reading Agreement for Diagnosis of the Chronic Cerebrospinal Venous Insufficiency in Patients with Multiple Sclerosis.Current neurovascular research · 2017Article
- Autonomic Dysregulation in Multiple Sclerosis.International journal of molecular sciences · 2015Review
- Validity of the diagnostic criteria for chronic cerebrospinal venous insufficiency and association with multiple sclerosis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014Article
- [Ultrahigh field MRI in context of neurological diseases].Der Nervenarzt · 2014Review
- Chronic cerebrospinal venous insufficiency and multiple sclerosis: a comprehensive meta-analysis of case-control studies.Therapeutic advances in neurological disorders · 2014Review
- Is there any relation between chronic cerebrospinal venous insufficiency and multiple sclerosis? - a critical review.Polish journal of radiology · 2014Review
- Ultrasonographic evaluation of cerebral arterial and venous haemodynamics in multiple sclerosis: a case-control study.PloS one · 2014Article
- Potential involvement of the extracranial venous system in central nervous system disorders and aging.BMC medicine · 2013Review
- No evidence for impairment of venous hemodynamics in children or young adults with pediatric-onset multiple sclerosis.AJNR. American journal of neuroradiology · 2013Article
- Article
- Mystery of chronic cerebrospinal venous insufficiency: identical venographic and ultrasound findings in patients with MS and controls.AJNR. American journal of neuroradiology · 2013Article
- The role of noninvasive and invasive diagnostic imaging techniques for detection of extra-cranial venous system anomalies and developmental variants.BMC medicine · 2013Review
- Chronic cerebrospinal venous insufficiency: case-control neurosonography results.Annals of neurology · 2013Article
- Evidence against the involvement of chronic cerebrospinal venous abnormalities in multiple sclerosis. A case-control study.PloS one · 2013Article
- Chronic cerebrospinal venous insufficiency is not associated with multiple sclerosis and its severity: a blind-verified study.PloS one · 2013Article
- Reply: To PMID 23370468.AJNR. American journal of neuroradiologyArticle
- Cerebral venous hemodynamic abnormalities in episodic and chronic migraine.Functional neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 14 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To systematically review the ultrasonographic criteria proposed for the diagnosis of chronic cerebrospinal venous insufficiency (CCSVI). The authors analyzed the five ultrasonographic criteria, four extracranial and one intracranial, suggested for the diagnosis of CCSVI in multiple sclerosis (MS), together with the references from which these criteria were derived and the main studies that explored the physiology of cerebrospinal drainage. The proposed CCSVI criteria are questionable due to both methodological and technical errors: criteria 1 and 3 are based on a scientifically incorrect application of data obtained in a different setting; criteria 2 and 4 have never been validated before; criterion 2 is technically incorrect; criteria 3 and 5 are susceptible to so many external factors that it is difficult to state whether the data collected are pathological or a variation from the normal. It is also unclear how it was decided that two or more of these five ultrasound criteria may be used to diagnose CCSVI, since no validation of these criteria was performed by different and independent observers nor were they blindly compared with a validated gold-standard investigation. The European Society of Neurosonology and Cerebral Hemodynamics (ESNCH) has considerable concerns regarding the accuracy of the proposed criteria for CCSVI in MS. Therefore, any potentially harmful interventional treatment such as transluminal angioplasty and/or stenting should be strongly discouraged.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.