Trial reportMedical science monitor : international medical journal of experimental and clinical research2012
Differences in endothelial function between Korean-Asians and Caucasians.
Trial report in Medical science monitor : international medical journal of experimental and clinical research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Effectiveness of Nursing and Non-Pharmacological Interventions in Reducing Intradialytic Hypotension Among Haemodialysis Patients: A Systematic Review and Meta-Analysis.Nursing open · 2026Pooled it
- Benefits and harms of extending the duration of dual antiplatelet therapy after percutaneous coronary intervention with drug-eluting stents: a meta-analysis.TheScientificWorldJournal · 2014Pooled it
- The effect of acute administration of vitamin D on micro vascular endothelial function in Caucasians and South Asian Indians.Medical science monitor : international medical journal of experimental and clinical research · 2013Trial
- CoQ10 and endothelial function in Asians from Korea compared to Asians born in the United States and US born Caucasians.Medical science monitor : international medical journal of experimental and clinical research · 2013Trial
- Protective effect of anti-oxidants on endothelial function in young Korean-Asians compared to Caucasians.Medical science monitor : international medical journal of experimental and clinical research · 2012Trial
- Blindspot: how sun exposure guidelines have ignored the health of individuals with skin of color.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Review
- Quantifying Erythema and Skin Tone Variation in Cutaneous Rashes: A Colorimetric Approach.Cureus · 2026Article
- Dermatology: how to manage rosacea in skin of colour.Drugs in context · 2022Review
- Effect of Tai Chi Combined with Mental Imagery on Cutaneous Microcirculatory Function and Blood Pressure in a Diabetic and Elderly Population.Healthcare (Basel, Switzerland) · 2020Article
- Endothelial Function in Healthy Young Individuals Is Associated with Dietary Consumption of Saturated Fat.Frontiers in physiology · 2017Article
- Acute Thermotherapy Prevents Impairments in Cutaneous Microvascular Function Induced by a High Fat Meal.Journal of diabetes research · 2016Article
- Anterior cruciate ligament elasticity and force for flexion during the menstrual cycle.Medical science monitor : international medical journal of experimental and clinical research · 2013Article
- What is more damaging to vascular endothelial function: Diabetes, age, high BMI, or all of the above?Medical science monitor : international medical journal of experimental and clinical research · 2013Article
- Resting blood flow in the skin: does it exist, and what is the influence of temperature, aging, and diabetes?Journal of diabetes science and technology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe vascular endothelium plays an integral role in maintaining vascular homeostasis, including the regulation of blood flow, vascular tone, and platelet aggregation. The aim of this study was to see if there were any differences in endothelial function between Koreans and Caucasians. MATERIAL/
methodsThis was accomplished by 2 measures of endothelial function--the response to local heat and the response to vascular occlusion. Ten Caucasian and 10 Korean male and female subjects participated (<35 years old). Endothelial function was assessed by the skin blood flow response to local heat using a thermode for 6 minutes at 3 temperatures (38°C, 40°C and 42°C) and by vascular occlusion for 4 minutes followed by release and measurement of skin blood flow for 2 minutes.
resultsWhen applying 6 minutes of local heat at 3 different temperatures (38°C, 40°C, and 42°C), the skin blood flows were significantly higher for all temperatures in Caucasians as compared with Koreans, with peak blood flow of 223±48.1, 413.7±132.1, and 517.4±135.8 flux in Caucasians and 126.4±41.3, 251±77.9, and 398±97.2 flux in Koreans, respectively (p=0.001). Results of this study support the idea that the skin blood flow response to occlusion was significantly higher in Caucasians (peak 411.9±88.9 flux) than Koreans (peak 332.4±75.8 flux) (p=0.016).
conclusionsThese findings suggest that Koreans may have lower endothelial function than Caucasians, which may be explained, in part, by genetic variations between the 2 ethnic groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.