Evidence map›Paper›PMID 22648202›Full record

ArticleEuropean journal of nutrition2013

Low-fat dairy, but not whole-/high-fat dairy, consumption is related with higher serum adiponectin levels in apparently healthy adults.

Kaijun Niu, Yoritoshi Kobayashi, Lei Guan, Haruki Monma, Hui Guo, Yufei Cui, Atsushi Otomo, Masahiko Chujo, Ryoichi Nagatomi

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Article in European journal of nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kaijun NiuDepartment of Epidemiology, School of Public Health, Tianjin Medical University, Heping District, Tianjin, People's Republic of China. nkj0809@gmail.com
Yoritoshi Kobayashi
Lei Guan
Haruki Monma
Hui Guo
Yufei Cui
Atsushi Otomo
Masahiko Chujo
Ryoichi Nagatomi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough previous studies suggested that higher low-fat dairy consumption lower the risk of type 2 diabetes, the mediating factors are not well understood. Higher baseline adiponectin levels are related with a lower risk of type 2 diabetes. This study evaluated whether low-fat dairy is related with adiponectin in apparently healthy adults.

methodsWe investigated a cross-sectional (n = 938) and one-year longitudinal (n = 759) relationship between low-fat and whole-/high-fat dairy (both including cow's milk and yogurt) and adiponectin. Dairy consumption was assessed with a validated food frequency questionnaire. Serum adiponectin was measured by using a specific sandwich enzyme-linked immunosorbent assay.

resultsIn the cross-sectional analysis, the geometric means (95 % confidence intervals [95 % CIs]) of log-transformed adiponectin related with the low-fat dairy categories were 7.27 (6.80-7.77) for the lowest category, 7.67 (7.09-8.31) for the middle category, and 8.40 (7.73-9.13) for the highest category (p < 0.001) after adjustment for potential confounders (including all lifestyle factors). In the longitudinal analysis, repeated-measures ANCOVA adjusted for confounding factors showed a significant time-by-categories (categories of low-fat dairy) interaction in the change of adiponectin. In contrast, no significant relationship was found between the whole-/high-fat dairy categories and adiponectin.

conclusionsThis study has shown that higher consumption of low-fat dairy, but not of whole-/high-fat dairy, is related with higher levels of adiponectin and with the change of adiponectin level at the one-year follow-up. These results suggest that the consumption of low-fat dairy may have a beneficial effect on serum adiponectin levels.

Indexed as

AdiponectinAdultBlood GlucoseBlood PressureBody Mass IndexCholesterol, HDLCholesterol, LDLCross-Sectional StudiesDairy ProductsDiabetes Mellitus, Type 2Dietary FatsEnzyme-Linked Immunosorbent AssayFemaleFollow-Up StudiesHumansLife StyleAdiponectinBlood GlucoseCholesterol, HDLCholesterol, LDLDietary Fats

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.