ArticleAutophagy2012
Not all autophagy is equal.
Article in Autophagy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- lncSNHG16 promotes hepatocellular carcinoma development by inhibiting autophagy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Article
- Review
- Rapamycin inhibits proliferation and induces autophagy in human neuroblastoma cells.Bioscience reports · 2018Article
- S100A4 promotes lung tumor development through β-catenin pathway-mediated autophagy inhibition.Cell death & disease · 2018Article
- EWS-FLI1 positively regulates autophagy by increasing ATG4B expression in Ewing sarcoma cells.International journal of molecular medicine · 2017Article
- Hinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1.Oncotarget · 2016Article
- Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells.Oncotarget · 2016Article
- Autophagy and Tubular Cell Death in the Kidney.Seminars in nephrology · 2016Review
- Autophagy in 5-Fluorouracil Therapy in Gastrointestinal Cancer: Trends and Challenges.Chinese medical journal · 2016Review
- MicroRNAs in clear cell renal cell carcinoma: biological functions and applications.Journal of kidney cancer and VHL · 2015Article
- Tumor suppressor gene PDCD4 negatively regulates autophagy by inhibiting the expression of autophagy-related gene ATG5.Autophagy · 2013Article
Corrections and comments
- Comment on
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Autophagy is an important mechanism in cancer cell survival and tumor growth and plays both pro- and anti-oncogenic roles. However, the biochemical basis for these diverse functions is not well understood. Our work provides new evidence for the existence of two separate autophagic programs regulated in an opposite manner by the von Hippel-Lindau tumor suppressor (VHL). These programs, marked by differential requirements for LC3B vs. LC3C, play tumor-promoting and tumor-suppressing roles in renal cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.