ArticleThe Analyst2012
Using a nanopore for single molecule detection and single cell transfection.
Article in The Analyst, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Single-molecule FRET and tracking of transfected biomolecules in living cells.Biophysical journal · 2026Article
- Recent advances in integrated solid-state nanopore sensors.Lab on a chip · 2021Review
- Resistive amplitude fingerprints during translocation of linear molecules through charged solid-state nanopores.The Journal of chemical physics · 2020Article
- Beyond mass spectrometry, the next step in proteomics.Science advances · 2020Review
- On-Chip Stretching, Sorting, and Electro-Optical Nanopore Sensing of Ultralong Human Genomic DNA.ACS nano · 2019Article
- Detection of methylation on dsDNA using nanopores in a MoSNanoscale · 2017Article
- Reading the primary structure of a protein with 0.07 nmNature nanotechnology · 2016Article
- Electro-optical detection of single λ-DNA.Chemical communications (Cambridge, England) · 2015Article
- Watching single proteins using engineered nanopores.Protein and peptide letters · 2014Review
- Suitable transfection methods for single particle tracing in plant suspension cells.Plant methods · 2014Article
- Microfluidic electroporation for cellular analysis and delivery.Lab on a chip · 2013Review
- Micro-/nanofluidics based cell electroporation.Biomicrofluidics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
We assert that it is possible to trap and identify proteins, and even (conceivably) manipulate proteins secreted from a single cell (i.e. the secretome) through transfection via electroporation by exploiting the exquisite control over the electrostatic potential available in a nanopore. These capabilities may be leveraged for single cell analysis and transfection with single molecule resolution, ultimately enabling a careful scrutiny of tissue heterogeneity.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.