Evidence map›Paper›PMID 22645705›Full record

ArticleCellular logistics2012

Searching for gold beyond mitosis: Mining intracellular membrane traffic in Aspergillus nidulans.

Miguel A Peñalva, Antonio Galindo, Juan F Abenza, Mario Pinar, Ana M Calcagno-Pizarelli, Herbert N Arst, Areti Pantazopoulou

Open access · bronzeAbstract read
In one paragraph

Article in Cellular logistics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Life and Death of Fungal Transporters under the Challenge of Polarity.International journal of molecular sciences · 2020
    Review
  11. Article
  12. Nuclear movement in fungi.Seminars in cell & developmental biology · 2018
    Review
  13. Article
  14. Article
  15. Cell Biology of Hyphal Growth.Microbiology spectrum · 2017
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Miguel A Peñalva
Antonio Galindo
Juan F Abenza
Mario Pinar
Ana M Calcagno-Pizarelli
Herbert N Arst
Areti Pantazopoulou
Consejo Superior de Investigaciones Científicas · ESCzech Academy of Sciences, Institute of Microbiology · CZ

Funding

Biotechnology and Biological Sciences Research Council BB/F01189X/1Wellcome Trust
6 · The paper itself

Abstract

The genetically tractable filamentous ascomycete fungus Aspergillus nidulans has been successfully exploited to gain major insight into the eukaryotic cell cycle. More recently, its amenability to in vivo multidimensional microscopy has fueled a potentially gilded second age of A. nidulans cell biology studies. This review specifically deals with studies on intracellular membrane traffic in A. nidulans. The cellular logistics are subordinated to the needs imposed by the polarized mode of growth of the multinucleated hyphal tip cells, whereas membrane traffic is adapted to the large intracellular distances. Recent work illustrates the usefulness of this fungus for morphological and biochemical studies on endosome and Golgi maturation, and on the role of microtubule-dependent motors in the long-distance movement of endosomes. The fungus is ideally suited for genetic studies on the secretory pathway, as mutations impairing secretion reduce apical extension rates, resulting in phenotypes detectable by visual inspection of colonies.

Identifiers

PMID22645705
PMCPMC3355971
OpenAlexW2006260182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.