ArticleBMJ (Clinical research ed.)2012
Relation between volume and outcome for patients with severe sepsis in United Kingdom: retrospective cohort study.
Article in BMJ (Clinical research ed.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Volume-Outcome Relationship in Critical Care: A Systematic Review and Meta-analysis.Chest · 2015Pooled it
- Impact of hospital sepsis case volume on mortality in sepsis patients: a meta-analysis.Frontiers in medicine · 2026Review
- Intensive Care Medicine in Portugal.Critical care science · 2025Article
- Article
- Impact of institutional case volume on intensive care unit mortality.Acute and critical care · 2023Article
- Association of Annual Intensive Care Unit Sepsis Caseload With Hospital Mortality From Sepsis in the United Kingdom, 2010-2016.JAMA network open · 2021Article
- The problems of smaller, rural and remote hospitals: Separating facts from fiction.Future healthcare journal · 2020Article
- Interhospital variation in mortality among patients with systemic lupus erythematosus and sepsis in the USA.Rheumatology (Oxford, England) · 2019Article
- Effect of Institutional Case Volume on In-Hospital and Long-Term Mortality in Critically Ill Patients Requiring Mechanical Ventilation for 48 Hours or More.Journal of Korean medical science · 2019Article
- PICU Volume and Outcome: A Severity-Adjusted Analysis.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2016Article
- Observational
- Volume-Mortality Relationships during Hospitalization with Severe Sepsis Exist Only at Low Case Volumes.Annals of the American Thoracic Society · 2015Article
- Temporal Changes in the Influence of Hospitals and Regional Healthcare Networks on Severe Sepsis Mortality.Critical care medicine · 2015Article
- Comparing mortality among adult, general intensive care units in England with varying intensivist cover patterns: a retrospective cohort study.Critical care (London, England) · 2014Article
- Association between hospital case volume and mortality in non-elderly pneumonia patients stratified by severity: a retrospective cohort study.BMC health services research · 2014Article
- Is the volume of mechanically ventilated admissions to UK critical care units associated with improved outcomes?Intensive care medicine · 2014Article
- Hospital case volume and outcomes among patients hospitalized with severe sepsis.American journal of respiratory and critical care medicine · 2014Article
- Renal transplantation: relationship between hospital/surgeon volume and postoperative severe sepsis/graft-failure. a nationwide population-based study.International journal of medical sciences · 2014Article
- Article
- What's new in ICU volume-outcome relationships?Intensive care medicine · 2013Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate whether a relation exists between volume and outcome for admissions with severe sepsis to adult general critical care units in the United Kingdom.
designRetrospective cohort study using data from a pooled case mix and outcome database.
settingAdult general critical care units participating in the case mix programme.
participantsConsecutive admissions to participating units for the years 2008-09 meeting objective, standardised criteria for severe sepsis.
main outcome measuresMortality at ultimate discharge from acute hospital.
resultsThe primary exposure was volume of admissions with severe sepsis per unit per year. A multivariable logistic regression analysis, using generalised estimating equations, was used to assess the association between volume, modelled using fractional polynomials, and ultimate acute hospital mortality while adjusting for potential confounders. No relation was seen between volume and outcome for admissions with severe sepsis to adult, general critical care units in the UK. Subgroup analyses tested for interactions between the effect of volume and acute severity of illness or receipt of mechanical ventilation. No significant interactions were found.
conclusionsThis study showed no relation between volume and outcome in admissions with severe sepsis treated in adult general critical care units in the UK.
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