ReviewCurrent allergy and asthma reports2012
Role of cockroach proteases in allergic disease.
Review in Current allergy and asthma reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Association of serum total IgE and allergen-specific IgE with insulin resistance in adolescents: an analysis of the NHANES database.BMC pediatrics · 2024Article
- Alternaria alternata-induced airway epithelial signaling and inflammatory responses via protease-activated receptor-2 expression.Biochemical and biophysical research communications · 2022Article
- Lung Inflammatory Response to Environmental Dust Exposure in Mice Suggests a Link to Regional Respiratory Disease Risk.Journal of inflammation research · 2021Article
- German Cockroach Extract Induces Matrix Metalloproteinase-1 Expression, Leading to Tight Junction Disruption in Human Airway Epithelial Cells.Yonsei medical journal · 2018Article
- Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.American journal of physiology. Lung cellular and molecular physiology · 2018Article
- House dust mite and Cockroach specific Immunoglobulin E sensitization is associated with diabetes mellitus in the adult Korean population.Scientific reports · 2018Article
- Association between Cockroach-specific Immunoglobulin E and periodontitis in Korean male adults Based on Korean National Health and Nutrition Examination Survey.Scientific reports · 2017Article
- Proteases in agricultural dust induce lung inflammation through PAR-1 and PAR-2 activation.American journal of physiology. Lung cellular and molecular physiology · 2015Article
- Protease-activated receptors and itch.Handbook of experimental pharmacology · 2015Review
- Modulation of airway epithelial antiviral immunity by fungal exposure.American journal of respiratory cell and molecular biology · 2014Article
- Hypersensitivity to aeroallergens in patients with nasobronchial allergy.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2014Article
- House dust mite interactions with airway epithelium: role in allergic airway inflammation.Current allergy and asthma reports · 2013Review
- Preparation and characterization of an extract of german cockroach from a korean source.Allergy, asthma & immunology research · 2013Article
- Functional interaction of cockroach allergens and mannose receptor (CD206) in human circulating fibrocytes.PloS one · 2013Article
- Assessment of environmental cockroach allergen exposure.Current allergy and asthma reports · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Allergic asthma is on the rise in developed countries, and cockroach exposure is a major risk factor for the development of asthma. In recent years, a number of studies have investigated the importance of allergen-associated proteases in modulating allergic airway inflammation. Many of the studies have suggested the importance of allergen-associated proteases as having a direct role on airway epithelial cells and dendritic cells. In most cases, activation of the protease activated receptor (PAR)-2 has been implicated as a mechanism behind the potent allergenicity associated with cockroaches. In this review, we focus on recent evidence linking cockroach proteases to activation of a variety of cells important in allergic airway inflammation and the role of PAR-2 in this process. We will highlight recent data exploring the potential mechanisms involved in the biological effects of the allergen.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.