ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2013
Glaucoma in penetrating keratoplasty: risk factors, management and outcome.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Incidence and risk factors for post-penetrating keratoplasty glaucoma: A systematic review and meta-analysis.PloS one · 2017Pooled it
- Evaluation and comparison of long-term outcomes of keratoplasty in adult and geriatric patient groups.BMC ophthalmology · 2026Article
- Advances in corneal transplantation.Eye (London, England) · 2025Review
- Prospective evaluation of iris-trabecular contact using anterior segment optical coherence tomography and early intraocular pressure changes in eyes following penetrating keratoplasty.BMC ophthalmology · 2025Article
- Mechanism and treatment of secondary glaucoma after corneal transplantation: a review.Frontiers in ophthalmology · 2024Review
- Efficacy and Safety of Ab-Interno Canaloplasty in Post-Keratoplasty Patients: 3-Year Results.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Incidence and risk factors for glaucoma development and progression after corneal transplantation.Eye (London, England) · 2023Article
- Surgical management of glaucoma following different keratoplasty techniques.International ophthalmology · 2022Article
- Gonioscopic angle evaluation and its correlation with graft survival and post-operative ocular hypertension in patients of Descemet's stripping endothelial keratoplasty.Indian journal of ophthalmology · 2022Article
- Anterior synechiae after penetrating keratoplasty in infants and children with Peters' anomaly.BMC ophthalmology · 2022Article
- Incidence and risk factors for post-penetrating keratoplasty glaucoma.Indian journal of ophthalmology · 2022Article
- Comparison of long-term outcomes of trabeculectomy and risk factors for failure in eyes post penetrating keratoplasty or Descemet's stripping endothelial keratoplasty.Indian journal of ophthalmology · 2022Article
- Intraocular Pressure Measurement after Penetrating Keratoplasty.Diagnostics (Basel, Switzerland) · 2022Review
- Incidence and Risk Factors of Ocular Hypertension/Glaucoma After Descemet Stripping Automated Endothelial Keratoplasty.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Comparative observation of the efficacy of simplified Descemet stripping endothelial keratoplasty and penetrating keratoplasty in treating bullous keratopathy.Experimental and therapeutic medicine · 2020Article
- Corneal graft melting: a systematic review.International journal of ophthalmology · 2020Review
- Glaucoma management after corneal transplantation surgeries.Current opinion in ophthalmology · 2016Review
- Comparison of Diaton transpalpebral tonometer with applanation tonometry in keratoconus.International journal of ophthalmology · 2016Article
- Incidence and risk factors for traumatic intraocular pressure elevation and traumatic glaucoma after open-globe injury.Eye (London, England) · 2015Observational
- Intraocular pressure elevation and post-DMEK glaucoma following Descemet membrane endothelial keratoplasty.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2014Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionGlaucoma is a leading cause for graft failure. This retrospective study analyzes the risk factors, graft status, and treatment modalities in patients with post-penetrating keratoplasty glaucoma.
methodsA retrospective analysis of case records of 1,848 penetrating keratoplasties carried out between 2000 and 2005 was performed. A total of 160 patients (160 eyes) with post-penetrating keratoplasty glaucoma were included; 112 cases were primary grafts, 48 repeated grafts. The assessment included the pre-operative history of corneal disease and glaucoma, the lens status, and the anesthesiological techniques. Furthermore, the response to anti-glaucoma treatment, graft failure, and endothelial cell loss was evaluated.
resultsThe incidence of post-penetrating keratoplasty glaucoma was 8.7 % (160/1,848). Preoperative glaucoma was the most important risk factor (62/160). Half of the patients (81 patients) responded to medical therapy (51 %) and the other half of patients (79 patients) to surgical therapy (49 %); of the latter, filtering surgery were performed in 16 %, cyclodestructive procedures in 66 % and both in 16 %. One patient received a glaucoma implant and cyclodestructive procedures (1 %). After 24 months, clear grafts were achieved in 94 eyes (59 %). Visual acuity after 24 months of 20/200 (logMAR 1.0) or better was achieved in 77 eyes (46 %) and of 20/50 (logMAR 0.4) in 33 eyes (21 %).
conclusionsCareful and ongoing observation of IOP, especially in the first year after PK, is recommended for patients after penetrating keratoplasty and prompt treatment of IOP elevation when indicated. Early filtering surgery with a better outcome than other surgery procedures should be preferred if medical treatment is not sufficient. Despite anti-glaucoma therapy, good visual outcome can remain beyond expectations despite a clear graft. While there is a potential option for graft exchange, damage to the optic nerve from end-stage glaucoma leads immutably to visual loss.
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