Trial reportArchives of orthopaedic and trauma surgery2012
Pathway-controlled fast-track rehabilitation after total knee arthroplasty: a randomized prospective clinical study evaluating the recovery pattern, drug consumption, and length of stay.
Trial report in Archives of orthopaedic and trauma surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Clinical practice guideline for physical therapist management of total knee arthroplasty: revision 2026.Physical therapy · 2026Guideline
- The efficacy of enhanced recovery program compared to routine care for patients undergoing knee replacement surgery: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Meta-analysis of comparative effects of mobile app-based digital rehabilitation versus traditional rehabilitation after total knee arthroplasty.Frontiers in physiology · 2025Pooled it
- Effectiveness of total knee arthroplasty rehabilitation programmes: A systematic review and meta-analysis.Journal of rehabilitation medicine · 2021Pooled it
- Prognostic factors for inpatient functional recovery following total hip and knee arthroplasty: a systematic review.Acta orthopaedica · 2020Pooled it
- An enhanced recovery after surgery program in orthopedic surgery: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2019Pooled it
- Enhanced recovery after surgery for hip and knee arthroplasty: a systematic review and meta-analysis.Postgraduate medical journal · 2017Pooled it
- Pooled it
- Post-operative limb position can influence blood loss and range of motion after total knee arthroplasty: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015Pooled it
- Effects of early virtual reality-based rehabilitation in patients with total knee arthroplasty: A randomized controlled trial.Medicine · 2020Trial
- Fast-track total knee arthroplasty improved clinical and functional outcome in the first 7 days after surgery: a randomized controlled pilot study with 5-year follow-up.Archives of orthopaedic and trauma surgery · 2018Trial
- Role of preoperative pain, muscle function, and activity level in discharge readiness after fast-track hip and knee arthroplasty.Acta orthopaedica · 2014Trial
- Enhanced recovery after surgery in older patients with total Knee Arthroplasty: A systematic review and meta-analysis.Journal of orthopaedics · 2025Review
- Does vasopressor administration in the ICU affect outcomes following primary total joint arthroplasty?Archives of orthopaedic and trauma surgery · 2025Article
- Association between preoperative anaemia and one year mortality risk in older patients undergoing femoral neck fracture surgery: an observational study.International orthopaedics · 2025Observational
- Association of self-efficacy, risk attitudes, and time preferences with health-related quality of life and functioning after total hip or knee replacement - Results of the MobilE-TRA 2 cohort.Health and quality of life outcomes · 2025Observational
- Handheld imageless robotic total knee arthroplasty improves accuracy and early clinical outcomes when compared with navigation.Arthroplasty (London, England) · 2025Article
- The factors determining early mobilization in elderly patients undergoing total knee replacement.BMC geriatrics · 2025Article
- Validation of a Novel Landmark-guided Intra-articular Postero-medial Surgeon-administered Injection Technique.Arthroplasty today · 2025Article
- What is the multifactorial efficacy of day-zero ambulation post-total hip replacement surgery: A systematic review.Journal of orthopaedics · 2025Review
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate fast-track rehabilitation concept in terms of a measurable effect on the early recovery after total knee arthroplasty (TKA).
methodsThis was an open, randomized, prospective clinical study, comparing the fast-track rehabilitation--a pathway-controlled early recovery program (Joint Care(®))--with standard postoperative rehabilitation care, after TKA. Overall, 147 patients had TKA (N = 74 fast-track rehabilitation, N = 73 standard rehabilitation). The fast-track rehabilitation patients received a group therapy, early mobilization (same day as surgery) and 1:1 physiotherapy (2 h/day). Patient monitoring occurred over 3 months (1 pre- and 4 post-operative visits). The standard rehabilitation group received individual postoperative care according to the existing protocol, with 1:1 physiotherapy (1 h/day). The cumulative American Knee Society Score (AKSS) was the primary evaluation variable, used to detect changes in joint function and perception of pain. The secondary evaluation variables were WOMAC index score, analgesic drug consumption, length of stay (LOS), and safety.
resultsAfter TKA, patients in the fast-track rehabilitation group showed enhanced recovery compared with the standard rehabilitation group, as based on the differences between the groups for the cumulative AKSS (p = 0.0003), WOMAC index score (<0.0001), reduced intake of concomitant analgesic drugs, reduced LOS (6.75 vs. 13.20 days, p < 0001), and lower number of adverse events.
conclusionFor TKA, implementation of pathway-controlled fast-track rehabilitation is achievable and beneficial as based on the AKSS and WOMAC score, reduced intake of analgesic drugs, and reduced LOS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.