Evidence map›Paper›PMID 22642858›Full record

Trial reportPsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2012

Isolating the role of psychological dysfunction in smoking cessation: relations of personality and psychopathology to attaining cessation milestones.

Adam M Leventhal, Sandra J Japuntich, Megan E Piper, Douglas E Jorenby, Tanya R Schlam, Timothy B Baker

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Anxiety Sensitivity and Distress Tolerance in Smokers: Relations With Tobacco Dependence, Withdrawal, and Quitting Success†.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Trial
  3. Trial
  4. Trial
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  7. Trial
  8. Article
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  15. The social networks of smokers attempting to quit: An empirically derived and validated classification.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2018
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Psychological symptoms, smoking lapse behavior, and the mediating effects of nicotine withdrawal symptoms: A laboratory study.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Adam M LeventhalDepartment of Preventive Medicine, University of Southern California Keck School of Medicine, 2250 Alcazar Street, CSC 240, Los Angeles, CA 90033, USA. adam.leventhal@usc.edu
Sandra J Japuntich
Megan E Piper
Douglas E Jorenby
Tanya R Schlam
Timothy B Baker
University of Wisconsin–Madison · USNational Center for Post Traumatic Stress Disorder · USUniversity of Southern California · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Enhancing the Effectiveness of Varenicline Based Smoking Cessation TreatmentR01HL109031 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TIMOTHY B, STEIN, JAMES H · 2011 to 2020
$17.5M
Institutional Clinical and Translational Science Award (UW-Madison)KL2RR025012 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$11.1M
Tobacco Dependence: Treatment and OutcomesP50DA019706 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TIMOTHY B · 2004 to 2008
$8.6M
Training in Translational Tobacco ScienceK05CA139871 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TIMOTHY B · 2008 to 2012
$850k
Influence of Nicotine on Positive and Negative Affect in Smokers with PTSDK08DA021311 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI COOK, JESSICA MEGAN · 2007 to 2011
$827k
Affective and Genetic Correlates of Amphetamine ResponseK08DA025041 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LEVENTHAL, ADAM MATTHEW · 2009 to 2013
$773k
NCATS NIH HHS UL1 TR000427NCI NIH HHS 1K05CA139871NCI NIH HHS K05 CA139871NCRR NIH HHS 1KL2RR025012-01NCRR NIH HHS 1UL1RR025011NCRR NIH HHS KL2 RR025012NCRR NIH HHS UL1 RR025011NHLBI NIH HHS R01 HL109031NIDA NIH HHS K08 DA021311NIDA NIH HHS K08DA021311NIDA NIH HHS K08DA02504NIDA NIH HHS K08 DA025041NIDA NIH HHS P50 DA019706NIDA NIH HHS P50DA019706
6 · The paper itself

Abstract

Research exploring psychological dysfunction as a predictor of smoking cessation success may be limited by nonoptimal predictor variables (i.e., categorical psychodiagnostic measures vs. continuous personality-based manifestations of dysfunction) and imprecise outcomes (i.e., summative point-prevalence abstinence vs. constituent cessation milestone measures). Accordingly, this study evaluated the unique and overlapping relations of broad-spectrum personality traits (positive emotionality, negative emotionality, and constraint) and past-year psychopathology (anxiety, mood, and substance use disorder) to point-prevalence abstinence and three smoking cessation milestones: (a) initiating abstinence, (b) first lapse, and (c) transition from lapse to relapse. Participants were daily smokers (N = 1365) enrolled in a smoking cessation treatment study. In single-predictor regression models, each manifestation of internalizing dysfunction (lower positive emotionality, higher negative emotionality, and anxiety and mood disorder) predicted failure at one or more cessation milestone(s). In simultaneous predictor models, lower positive and higher negative emotionality significantly predicted failure to achieve milestones after controlling for psychopathology. Psychopathology did not predict any outcome when controlling for personality. Negative emotionality showed the most robust and consistent effects, significantly predicting failure to initiate abstinence, earlier lapse, and lower point-prevalence abstinence rates. Substance use disorder and constraint did not predict cessation outcomes, and no single variable predicted lapse-to-relapse transition. These findings suggest that personality-related manifestations of internalizing dysfunction are more accurate markers of affective sources of relapse risk than mood and anxiety disorders. Further, individuals with high trait-negative emotionality may require intensive intervention to promote the initiation and early maintenance of abstinence.

Indexed as

PersonalityAdultBupropionCounselingDefense MechanismsFemaleHumansMaleMental DisordersNicotinePsychiatric Status Rating ScalesRecurrenceSmokingSmoking CessationSurveys and QuestionnairesTobacco Use DisorderBupropionNicotine

Identifiers

PMID22642858
PMCPMC3445746
OpenAlexW2126711514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.