ArticlePediatrics2012
Approach to infants born at 22 to 24 weeks' gestation: relationship to outcomes of more-mature infants.
Article in Pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
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Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Maternal COVID-19 infection and risk of respiratory distress syndrome among newborns: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- Ichthyosis Prematurity Syndrome: A Systematic Review of the Literature.Pediatric dermatologyPooled it
- Maternal Outcomes Among Periviable Births by Cesarean Delivery.JAMA network open · 2026Article
- Intensity of perinatal care for extreme preterm births and neurodevelopmental outcomes at age 5½: the EPIPAGE-2 cohort study.BMJ paediatrics open · 2025Article
- Article
- Systematic Quantitative Analysis of Fetal Dexamethasone Exposure and Fetal Lung Maturation in Pregnant Animals: Model Informed Dexamethasone Precision Dose Study.ACS pharmacology & translational science · 2024Article
- Association of Active Postnatal Care With Infant Survival Among Periviable Infants in the US.JAMA network open · 2023Article
- Lung surfactant as a biophysical assay for inhalation toxicology.Current research in toxicology · 2023Review
- Does active treatment in infants born at 22-23 weeks correlate with outcomes of more mature infants at the same hospital? An analysis of California NICU data, 2015-2019.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- Evaluation of the social skills of low birthweight infants using the Interaction Rating Scale.Journal of physical therapy science · 2022Article
- Changes Overtime in Perinatal Management and Outcomes of Extremely Preterm Infants in One Tertiary Care Romanian Center.Medicina (Kaunas, Lithuania) · 2022Article
- Non-invasive administration of poractant-α in neonatal respiratory distress syndrome via a supraglottic device in the clinical practice in a second level neonatal unit: comparison of LMA® vs iGel® devices.Acta bio-medica : Atenei Parmensis · 2022Article
- Disparities in the use of antenatal corticosteroids among women with hypertension in North Carolina.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Intensity of perinatal care for extremely preterm babies and outcomes at a higher gestational age: evidence from the EPIPAGE-2 cohort study.BMC pediatrics · 2020Article
- Article
- Mortality rate-dependent variations in the survival without major morbidities rate of extremely preterm infants.Scientific reports · 2019Article
- Article
- Neonatal Outcomes of Very Low Birth Weight Infants in Korean Neonatal Network from 2013 to 2016.Journal of Korean medical science · 2019Article
- The Prevalence of Complications of Prematurity among 1000 Newborns in Isfahan, Iran.Advanced biomedical research · 2019Article
- Feeding Practices in Very Preterm and Very Low Birth Weight Infants in an Area Where a Network of Human Milk Banks Is in Place.Frontiers in pediatrics · 2018Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
objectiveWe sought to determine if a center's approach to care of premature infants at the youngest gestational ages (22-24 weeks' gestation) is associated with clinical outcomes among infants of older gestational ages (25-27 weeks' gestation).
methodsInborn infants of 401 to 1000 g birth weight and 22 0/7 to 27 6/7 weeks' gestation at birth from 2002 to 2008 were enrolled into a prospectively collected database at 20 centers participating in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Markers of an aggressive approach to care for 22- to 24-week infants included use of antenatal corticosteroids, cesarean delivery, and resuscitation. The primary outcome was death before postnatal day 120 for infants of 25 to 27 weeks' gestation. Secondary outcomes were the combined outcomes of death or a number of morbidities associated with prematurity.
resultsOur study included 3631 infants 22 to 24 weeks' gestation and 5227 infants 25 to 27 weeks' gestation. Among the 22- to 24-week infants, use of antenatal corticosteroids ranged from 28% to 100%, cesarean delivery from 13% to 65%, and resuscitation from 30% to 100% by center. Centers with higher rates of antenatal corticosteroid use in 22- to 24-week infants had reduced rates of death, death or retinopathy of prematurity, death or late-onset sepsis, death or necrotizing enterocolitis, and death or neurodevelopmental impairment in 25- to 27-week infants.
conclusionsThis study suggests that physicians' willingness to provide care to extremely low gestation infants as measured by frequency of use of antenatal corticosteroids is associated with improved outcomes for more-mature infants.
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