Evidence map›Paper›PMID 22641221›Full record

ArticleNanoscale2012

Biomimetic monolayer-protected gold nanoparticles for immunorecognition.

Kellen M Harkness, Brian N Turner, Amanda C Agrawal, Yibin Zhang, John A McLean, David E Cliffel

Abstract read
In one paragraph

Article in Nanoscale, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Dendrimers as Modulators of Brain Cells.Molecules (Basel, Switzerland) · 2020
    Review
  2. Article
  3. Article
  4. A Bifunctional Spin Label for Ligand Recognition on Surfaces.Angewandte Chemie (International ed. in English) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kellen M HarknessDepartment of Chemistry, Vanderbilt Institute of Chemical Biology, Vanderbilt Institute for Integrative Biosystems Research and Education, Vanderbilt University, 7330 Stevenson Center, Station B 351822, Nashville, TN37235, USA.
Brian N Turner
Amanda C Agrawal
Yibin Zhang
John A McLean
David E Cliffel

Funding

Chemistry-Biology Interface Training GrantT32GM065086 · NIGMS · VANDERBILT UNIVERSITY · PI BACHMANN, BRIAN O, SULIKOWSKI, GARY ALLEN · 2002 to 2022
$7.0M
Elucidation of Leukocyte and Macrophage Biomarker Signatures from Drugs of AbuseRC2DA028981 · NIDA · VANDERBILT UNIVERSITY · PI LIPSON, HOD, MCLEAN, JOHN ALAN · 2009 to 2010
$2.7M
Epitope Discovery via Nanocluster PresentationR01GM076479 · NIGMS · VANDERBILT UNIVERSITY · PI CLIFFEL, DAVID E · 2006 to 2010
$1.4M
NIDA NIH HHS RC2 DA028981NIDA NIH HHS RC2DA028981NIGMS NIH HHS GM076479NIGMS NIH HHS R01 GM076479NIGMS NIH HHS T32 GM065086
6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) protected by self-assembled monolayers (SAMs) are capable of presenting precisely engineered surfaces at the nanoscale, allowing the mimicry of biomacromolecules on an artificial platform. Here we review the generation, characterization, and applications of monolayer-protected AuNPs that have been designed for immunorecognition by the integration of an oligopeptide epitope into the protecting monolayer. The resulting peptide-AuNP conjugate is an effective platform for biomimesis, as demonstrated by multiple studies. Recent work is presented and future directions for this field of research are discussed.

Indexed as

AnimalsAntibodiesAntigensBiomimetic MaterialsEpitopesGoldMetal NanoparticlesMicePeptidesTissue DistributionAntibodiesAntigensEpitopesGoldPeptides

Identifiers

PMID22641221
PMCPMC3376232

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.