Evidence map›Paper›PMID 22641203›Full record

ArticleNature genetics2012

Exploring the variation within.

Evan Z Macosko, Steven A McCarroll

Abstract readNewsComment
PubMed Publisher
In one paragraph

Article in Nature genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Frontiers in genetics · 2022
    Review
  3. Article
  4. It is time to take timing seriously in clinical genetics.European journal of human genetics : EJHG · 2015
    Article
  5. Review
  6. Article
  7. Somatic alpha-synuclein mutations in Parkinson's disease: hypothesis and preliminary data.Movement disorders : official journal of the Movement Disorder Society · 2013
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Evan Z Macosko
Steven A McCarroll

Funding

Fostering Research Mentorship & Training during Psychiatry Residency SupplementR25MH094612 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FAVA, MAURIZIO, GREENFIELD, SHELLY F. · 2011 to 2022
$2.3M
NIMH NIH HHS R25 MH094612
6 · The paper itself

Abstract

We usually think of an individual's cells as sharing the same genome. Challenging this notion, two new studies show that somatic mosaicism is common and can be an early herald of cancer.

Indexed as

Chromosome AberrationsMosaicismAgingFemaleHumansMaleNeoplasms

Identifiers

PMID22641203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.