Evidence map›Paper›PMID 22640714›Full record

ArticleObstetrics and gynecology clinics of North America2012

Endometrial cancer.

Kimberly K Leslie, Kristina W Thiel, Michael J Goodheart, Koen De Geest, Yichen Jia, Shujie Yang

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Obstetrics and gynecology clinics of North America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05427058 (Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05427058 narecruitingnot on this mapstarted 2024, after this paper: background citation

Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management: A Randomized Controlled Trial of Efficacy and Safety

TypeinterventionalSponsorUniversity of BrawijayaRan2024 to 2026Enrolled36ConditionsCervical Cancer, Endometrial CancerArmsSuperior Hypogastric Plexus Block, Ganglion Impar Block
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Laparotomic versus robotic surgery in elderly patients with endometrial cancer: A systematic review and meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Unraveling the Potential Role of NEDD4-like E3 Ligases in Cancer.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Observational
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. GPER modulators: Opportunity Nox on the heels of a class Akt.The Journal of steroid biochemistry and molecular biology · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kimberly K LeslieDepartment of Obstetrics and Gynecology, University of Iowa, Iowa City, IA 52242, USA. kimberly-leslie@uiowa.edu
Kristina W Thiel
Michael J Goodheart
Koen De Geest
Yichen Jia
Shujie Yang
University of Iowa · US

Funding

GYNECOLOGIC ONCOLOGY GROUP HEADQUARTERSU10CA027469 · NCI · GYNECOLOGIC ONCOLOGY GROUP · PI DISAIA, PHILIP J. · 1985 to 2013
$132.6M
Targeted Therapy for Endometrial CancerR01CA099908 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LESLIE, KIMBERLY K. · 2002 to 2023
$5.8M
NCI NIH HHS CA27469NCI NIH HHS CA99908NCI NIH HHS R01 CA099908NCI NIH HHS U10 CA027469
6 · The paper itself

Abstract

Despite the questions and barriers, the incorporation of molecular therapy into treatment regimens in endometrial cancer is an exciting area of investigation with the potential to improve outcomes. Outside of the development of a reliable screening test for endometrial cancer, converting the disease to a chronic state and improving progression-free survival is our best hope to reverse the concerning trend of decreasing 5-year survival for this disease.

Indexed as

Endometrial NeoplasmsHysterectomyMolecular Targeted TherapyAgedAntineoplastic Combined Chemotherapy ProtocolsChemotherapy, AdjuvantFemaleHumansLymph Node ExcisionMiddle AgedObesityPostmenopausePrognosisRisk FactorsUnited StatesUterine Hemorrhage

Identifiers

PMID22640714
PMCPMC3518445
OpenAlexW4232787766

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.