ArticleInternational wound journal2012
Multidrug-resistant organisms, wounds and topical antimicrobial protection.
Article in International wound journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 74 citations in OpenAlex.
- Injectable nanocomposite hydrogels for targeted intervention in cancer, wound healing, and bone and myocardial tissue engineering.Drug delivery and translational research · 2025Review
- Antibiotic resistance and biofilm formation inJournal of family medicine and primary care · 2025Article
- In Situ Hydrogel Formulation for Advanced Wound Dressing: Influence of Co-Solvents and Functional Excipient on Tailored Alginate-Pectin-Chitosan Blend Gelation Kinetics, Adhesiveness, and Performance.Gels (Basel, Switzerland) · 2023Article
- Titanium Dioxide Nano-Formulation: Characterization, Antimicrobial Activity, and Wound Healing in Animals.Animals : an open access journal from MDPI · 2023Article
- Therapeutic applications of nanobiotechnology.Journal of nanobiotechnology · 2023Review
- Silver Nanoparticles Phytofabricated throughAntibiotics (Basel, Switzerland) · 2023Article
- Bacterial Interactions in the Context of Chronic Wound Biofilm: A Review.Microorganisms · 2022Review
- A Novel Three-Polysaccharide Blend In Situ Gelling Powder for Wound Healing Applications.Pharmaceutics · 2021Article
- Antimicrobial, Antibiofilm, and Antioxidant Properties ofFrontiers in nutrition · 2021Article
- Biofilm exacerbates antibiotic resistance: Is this a current oversight in antimicrobial stewardship?Antimicrobial resistance and infection control · 2020Review
- A prospective evaluation of methylene blue and gentian violet dressing for management of chronic wounds with local infection.International wound journal · 2017Article
- Investigation and analysis of the characteristics and drug sensitivity of bacteria in skin ulcer infections.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2017Article
- Clinical safety and effectiveness evaluation of a new antimicrobial wound dressing designed to manage exudate, infection and biofilm.International wound journal · 2017Article
- In Vitro Assessment of the Antibacterial Potential of Silver Nano-Coatings on Cotton Gauzes for Prevention of Wound Infections.Materials (Basel, Switzerland) · 2016Article
- Enhanced Performance and Mode of Action of a Novel Antibiofilm Hydrofiber® Wound Dressing.BioMed research international · 2016Article
- Article
- Methylene Blue-Loaded Dissolving Microneedles: Potential Use in Photodynamic Antimicrobial Chemotherapy of Infected Wounds.Pharmaceutics · 2015Article
- The effect and safety of dressing composed by nylon threads covered with metallic silver in wound treatment.International wound journal · 2014Article
- The use of platensimycin and platencin to fight antibiotic resistance.Infection and drug resistance · 2013Review
- Anti-microbial, anti-biofilm activities and cell selectivity of the NRC-16 peptide derived from witch flounder, Glyptocephalus cynoglossus.Marine drugs · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multidrug-resistant organisms (MDROs) are increasingly implicated in both acute and chronic wound infections. The limited therapeutic options are further compromised by the fact that wound bacteria often co-exist within a biofilm community which enhances bacterial tolerance to antibiotics. As a consequence, topical antiseptics may be an important consideration for minimising the opportunity for wound infections involving MDROs. The objective of this research was to investigate the antimicrobial activity of a silver-containing gelling fibre dressing against a variety of MDROs in free-living and biofilm states, using stringent in vitro models designed to simulate a variety of wound conditions. MDROs included Acinetobacter baumannii, community-associated methicillin-resistant Staphylococcus aureus, and extended-spectrum beta-lactamase-producing bacteria. Clostridium difficile was also included in the study because it carries many of the characteristics seen in MDROs and evidence of multidrug resistance is emerging. Sustained in vitro antimicrobial activity of the silver-containing dressing was shown against 10 MDROs in a simulated wound fluid over 7 days, and inhibitory and bactericidal effects against both free-living and biofilm phenotypes were also consistently shown in simulated colonised wound surface models. The in vitro data support consideration of the silver-containing gelling fibre dressing as part of a protocol of care in the management of wounds colonised or infected with MDROs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.