Evidence map›Paper›PMID 22639986›Full record

ArticleAIDS care2013

Prospective prediction of viral suppression and immune response nine months after ART initiation in Seattle, WA.

Jane M Simoni, Samantha S Yard, David Huh

Abstract read
In one paragraph

Article in AIDS care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jane M SimoniDepartment of Psychology, University of Washington, Seattle, USA. jsimoni@uw.edu
Samantha S Yard
David Huh

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Florian Hladik · 1988 to 2026
$104.9M
PEER SUPPORT TO ENHANCE ANTIRETROVIRAL ADHERENCER01MH058986 · NIMH · YESHIVA UNIVERSITY · PI SIMONI, JANE MARIE · 1999 to 2006
$2.8M
Mentoring Diverse Scientists in Global HIV Research on Mental Health & AdherenceK24MH093243 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2011 to 2014
$590k
NIAID NIH HHS P30 AI0,27,757NIAID NIH HHS P30 AI027757NIMH NIH HHS K24 MH0,93,243NIMH NIH HHS K24 MH093243NIMH NIH HHS R01 MH058986
6 · The paper itself

Abstract

Knowing at antiretroviral therapy (ART) initiation which patients might be at greatest risk for failure to achieve viral suppression would enable providers to target patients most in need and tailor their care appropriately. This study involved multilevel modeling of data from a randomized controlled trial among outpatients in Seattle, WA, USA. The 224 participants initiating or switching ART at baseline were 24% female, 34% heterosexual, and 47% Caucasian. Of 24 baseline demographic and psychosocial patient-level variables modeled in separate generalized estimating equations, only employment predicted changes in HIV-1 RNA viral load or CD4 lymphocyte count over the course of the 9-month trial. Although the findings require replication, they suggest adherence support strategies should emphasize close monitoring and support for all patients initiating ART.

Indexed as

Antiretroviral Therapy, Highly ActiveAdultAnti-HIV AgentsCD4 Lymphocyte CountFemaleHIV-1HIV InfectionsHumansMaleMedication AdherenceMiddle AgedPredictive Value of TestsProspective StudiesQuality of LifeRNA, ViralSocioeconomic FactorsAnti-HIV AgentsRNA, Viral

Identifiers

PMID22639986
PMCPMC3584165

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.