Evidence map›Paper›PMID 22639702›Full record

ArticleElectronic journal of statistics2012

Structured penalties for functional linear models-partially empirical eigenvectors for regression.

Timothy W Randolph, Jaroslaw Harezlak, Ziding Feng

Abstract read
In one paragraph

Article in Electronic journal of statistics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Connectivity-informed adaptive regularization for generalized outcomes.The Canadian journal of statistics = Revue canadienne de statistique · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. KERNEL-PENALIZED REGRESSION FOR ANALYSIS OF MICROBIOME DATA.The annals of applied statistics · 2018
    Article
  8. Methods for scalar-on-function regression.International statistical review = Revue internationale de statistique · 2017
    Article
  9. Article
  10. Penalized nonparametric scalar-on-function regression via principal coordinates.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2017
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timothy W RandolphFred Hutchinson Cancer Research Center, Biostatistics and Biomathematics Program, Seattle, WA 98109.
Jaroslaw Harezlak
Ziding Feng

Funding

EDRN--DATA MANAGEMENT AND COORDINATING CENTERU01CA086368 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI FENG, ZIDING · 2000 to 2010
$16.9M
PROTON MRS STUDIES OF CEREBRAL INJURY IN HIV INFECTIONR01NS036524 · NINDS · TUFTS UNIVERSITY BOSTON · PI NAVIA, BRADFORD · 1997 to 2009
$12.9M
Use of Biomarkers in Diagnosis, Prognosis, Risk Prediction and Early Detection ofP01CA053996 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PRENTICE, ROSS L · 1991 to 2015
$9.4M
National NeuroAIDS Tissue Consortium Statistics and Data Coordinating CenterU01MH083545 · NIMH · INDIANA UNIVERSITY INDIANAPOLIS · PI YIANNOUTSOS, CONSTANTIN THEODORE · 2008 to 2012
$3.3M
Quantitative Methods for Spectral and Image Data in Proteomics ResearchR01CA126205 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI RANDOLPH, TIMOTHY W · 2006 to 2010
$1.3M
NCI NIH HHS P01 CA053996NCI NIH HHS R01 CA126205NCI NIH HHS U01 CA086368NIMH NIH HHS U01 MH083545NINDS NIH HHS R01 NS036524
6 · The paper itself

Abstract

One of the challenges with functional data is incorporating geometric structure, or local correlation, into the analysis. This structure is inherent in the output from an increasing number of biomedical technologies, and a functional linear model is often used to estimate the relationship between the predictor functions and scalar responses. Common approaches to the problem of estimating a coefficient function typically involve two stages: regularization and estimation. Regularization is usually done via dimension reduction, projecting onto a predefined span of basis functions or a reduced set of eigenvectors (principal components). In contrast, we present a unified approach that directly incorporates geometric structure into the estimation process by exploiting the joint eigenproperties of the predictors and a linear penalty operator. In this sense, the components in the regression are 'partially empirical' and the framework is provided by the generalized singular value decomposition (GSVD). The form of the penalized estimation is not new, but the GSVD clarifies the process and informs the choice of penalty by making explicit the joint influence of the penalty and predictors on the bias, variance and performance of the estimated coefficient function. Laboratory spectroscopy data and simulations are used to illustrate the concepts.

Identifiers

PMID22639702
PMCPMC3358792

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.