ArticleFrontiers in plant science2012
myo-Inositol Oxygenase is Required for Responses to Low Energy Conditions in Arabidopsis thaliana.
Article in Frontiers in plant science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 46 citations in OpenAlex.
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- Characterization ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Potential of engineering the myo-inositol oxidation pathway to increase stress resilience in plants.Molecular biology reports · 2022Review
- Zebularine, a DNA Methylation Inhibitor, Activates Anthocyanin Accumulation in Grapevine Cells.Genes · 2022Article
- Transcriptomic Analysis of theGenes · 2021Article
- Fungicidal Activity of Recombinant Javanicin againstMolecules (Basel, Switzerland) · 2021Article
- Molecular Targets and Biological Functions of cAMP Signaling inBiomolecules · 2021Article
- Genome-wide identification of the MIOX gene family and their expression profile in cotton development and response to abiotic stress.PloS one · 2021Article
- Biosynthesis and Transport of Nucleotide Sugars for Plant Hemicellulose.Frontiers in plant science · 2021Review
- Mechanisms underlying the enhanced biomass and abiotic stress tolerance phenotype of an Arabidopsis MIOX over-expresser.Plant direct · 2019Article
- Characterization of TwoReactive oxygen species (Apex, N.C.) · 2017Article
- Skewing in Arabidopsis roots involves disparate environmental signaling pathways.BMC plant biology · 2017Article
- The Interplay between Carbon Availability and Growth in Different Zones of the Growing Maize Leaf.Plant physiology · 2016Article
- Transcriptomic Profiling Analysis of Arabidopsis thaliana Treated with Exogenous Myo-Inositol.PloS one · 2016Article
- Ectopic Expression of a Glycine soja myo-Inositol Oxygenase Gene (GsMIOX1a) in Arabidopsis Enhances Tolerance to Alkaline Stress.PloS one · 2015Article
- Arabidopsis PHOSPHATE TRANSPORTER1 genes PHT1;8 and PHT1;9 are involved in root-to-shoot translocation of orthophosphate.BMC plant biology · 2014Article
- Elevating vitamin C content via overexpression ofIn vitro cellular & developmental biology. Plant : journal of the Tissue Culture Association · 2013Article
- Lipid signaling in plants.Frontiers in plant science · 2013Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
myo-Inositol is a precursor for cell wall components, is used as a backbone of myo-inositol trisphosphate (Ins(1,4,5)P(3)) and phosphatidylinositol phosphate signaling molecules, and is debated about whether it is also a precursor in an alternate ascorbic acid synthesis pathway. Plants control inositol homeostasis by regulation of key enzymes involved in myo-inositol synthesis and catabolism. Recent transcriptional profiling data indicate up-regulation of the myo-inositol oxygenase (MIOX) genes under conditions in which energy or nutrients are limited. To test whether the MIOX genes are required for responses to low energy, we first examined MIOX2 and MIOX4 gene expression regulation by energy/nutrient conditions. We found that both MIOX2 and MIOX4 expression are suppressed by exogenous glucose addition in the shoot, but not in the root. Both genes were abundantly expressed during low energy/nutrient conditions. Loss-of-function mutants in MIOX genes contain alterations in myo-inositol levels and growth changes in the root. Miox2 mutants can be complemented with a MIOX2:green fluorescent protein fusion. Further we show here that MIOX2 is a cytoplasmic protein, while MIOX4 is present mostly in the cytoplasm, but also occasionally in the nucleus. Together, these data suggest that MIOX catabolism in the shoot may influence root growth responses during low energy/nutrient conditions.
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