ArticleFrontiers in plant science2011
Plant Lessons: Exploring ABCB Functionality Through Structural Modeling.
Article in Frontiers in plant science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 50 citations in OpenAlex.
- Review
- The grapevine ABC transporter B family member 15 is aFrontiers in plant science · 2024Article
- Functional analysis revealed the involvement of ZmABCB15 in resistance to rice black-streaked dwarf virus infection.BMC plant biology · 2022Article
- Auxin Transporters-A Biochemical View.Cold Spring Harbor perspectives in biology · 2022Review
- Loss of Multiple ABCB Auxin Transporters Recapitulates the MajorFrontiers in plant science · 2022Article
- 2021 update on ATP-binding cassette (ABC) transporters: how they meet the needs of plants.Plant physiology · 2021Review
- Biospektrum : Zeitschrift der Gesellschaft fur Biologishe Chemie (GBCH) und der Vereinigung fur Allgemeine und Angewandte Mikrobiologie (VAAM) · 2021Article
- Improvement of a Genetic Transformation System and Preliminary Study on the Function ofInternational journal of molecular sciences · 2020Article
- Auxin-transporting ABC transporters are defined by a conserved D/E-P motif regulated by a prolylisomerase.The Journal of biological chemistry · 2020Article
- Plasma membrane receptor-like kinases and transporters are associated with 2,4-D resistance in wild radish.Annals of botany · 2020Article
- Molecular Characterization of Auxin Efflux Carrier- ABCB1 in hexaploid wheat.Scientific reports · 2019Article
- The Nuts and Bolts of PIN Auxin Efflux Carriers.Frontiers in plant science · 2019Review
- The Arabidopsis ATP-BINDING CASSETTE Transporter ABCB21 Regulates Auxin Levels in Cotyledons, the Root Pericycle, and Leaves.Frontiers in plant science · 2019Article
- Weed resistance to synthetic auxin herbicides.Pest management science · 2018Review
- Towards Identification of the Substrates of ATP-Binding Cassette Transporters.Plant physiology · 2018Review
- Plant hormone transporters: what we know and what we would like to know.BMC biology · 2017Review
- Plant membranes and border control.Journal of experimental botany · 2017Article
- 2,4-D resistance in wild radish: reduced herbicide translocation via inhibition of cellular transport.Journal of experimental botany · 2016Article
- TWISTED DWARF1 Mediates the Action of Auxin Transport Inhibitors on Actin Cytoskeleton Dynamics.The Plant cell · 2016Article
- The ABC of Phytohormone Translocation.Planta medica · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In contrast to mammalian ABCB1 proteins, narrow substrate specificity has been extensively documented for plant orthologs shown to catalyze the transport of the plant hormone, auxin. Using the crystal structures of the multidrug exporters Sav1866 and MmABCB1 as templates, we have developed structural models of plant ABCB proteins with a common architecture. Comparisons of these structures identified kingdom-specific candidate substrate-binding regions within the translocation chamber formed by the transmembrane domains of ABCBs from the model plant Arabidopsis. These results suggest an early evolutionary divergence of plant and mammalian ABCBs. Validation of these models becomes a priority for efforts to elucidate ABCB function and manipulate this class of transporters to enhance plant productivity and quality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.