ArticleFrontiers in plant science2011
Aldehyde Dehydrogenases in Arabidopsis thaliana: Biochemical Requirements, Metabolic Pathways, and Functional Analysis.
Article in Frontiers in plant science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed, 117 citations in OpenAlex.
- Ectopic Expression of ScALDH21 From a Desert Moss Enhances Cotton Resistance to Verticillium Wilt via the Modulation of Jasmonates and Phenylpropanoid Pathways.Plant biotechnology journal · 2026Article
- Integrative expression profiling and comparative bioinformatics analysis of ALDH7A1 in chickpea (Cicer arietinum L.) under salt and ABA treatments.BMC plant biology · 2026Article
- Identification of Aldehyde Dehydrogenase Gene Family inInternational journal of molecular sciences · 2025Article
- Functional characterization ofBiochemistry and biophysics reports · 2024Article
- Genome-wide identification and analysis of the cotton ALDH gene family.BMC genomics · 2024Article
- Comprehensive analysis of the aldehyde dehydrogenase gene family inFrontiers in plant science · 2024Article
- Roles of Reactive Carbonyl Species (RCS) in Plant Response to Abiotic Stress.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Redox Regulation of Salt Tolerance inInternational journal of molecular sciences · 2023Article
- GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants.Metabolites · 2023Review
- Article
- Bioenergetics of pollen tube growth in Arabidopsis thaliana revealed by ratiometric genetically encoded biosensors.Nature communications · 2022Article
- Molecular Breeding and Drought Tolerance in Chickpea.Life (Basel, Switzerland) · 2022Review
- Advanced pathway engineering for phototrophic putrescine production.Plant biotechnology journal · 2022Article
- Ubiquitome profiling reveals a regulatory pattern of UPL3 with UBP12 on metabolic-leaf senescence.Life science alliance · 2022Article
- Aldehyde dehydrogenase superfamily in sorghum: genome-wide identification, evolution, and transcript profiling during development stages and stress conditions.BMC plant biology · 2022Article
- Multi-Objective Optimization of Microalgae Metabolism: An Evolutive Algorithm Based on FBA.Metabolites · 2022Article
- Dissecting the Molecular Regulation of Natural Variation in Growth and Senescence of TwoInternational journal of molecular sciences · 2022Article
- Functional study ofFrontiers in plant science · 2022Article
- Comparative genomic analysis of the aldehyde dehydrogenase gene superfamily inFrontiers in plant science · 2022Article
- Aldehyde Dehydrogenase 3 Is an Expanded Gene Family with Potential Adaptive Roles in Chickpea.Plants (Basel, Switzerland) · 2021Article
3 more citing papers are in PubMed but not listed here.
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5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aldehyde dehydrogenases (ALDHs) are a family of enzymes which catalyze the oxidation of reactive aldehydes to their corresponding carboxylic acids. Here we summarize molecular genetic and biochemical analyses of selected ArabidopsisALDH genes. Aldehyde molecules are very reactive and are involved in many metabolic processes but when they accumulate in excess they become toxic. Thus activity of aldehyde dehydrogenases is important in regulating the homeostasis of aldehydes. Overexpression of some ALDH genes demonstrated an improved abiotic stress tolerance. Despite the fact that several reports are available describing a role for specific ALDHs, their precise physiological roles are often still unclear. Therefore a number of genetic and biochemical tools have been generated to address the function with an emphasis on stress-related ALDHs. ALDHs exert their functions in different cellular compartments and often in a developmental and tissue specific manner. To investigate substrate specificity, catalytic efficiencies have been determined using a range of substrates varying in carbon chain length and degree of carbon oxidation. Mutational approaches identified amino acid residues critical for coenzyme usage and enzyme activities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.