ArticleFrontiers in plant science2011
From models to crop species: caveats and solutions for translational metabolomics.
Article in Frontiers in plant science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Metabolomics to understand metabolic regulation underpinning fruit ripening, development, and quality.Journal of experimental botany · 2024Review
- Kiwifruit Metabolomics-An Investigation of within Orchard Metabolite Variability of Two Cultivars ofMetabolites · 2021Article
- Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices.Nature methods · 2021Review
- Photorespiration: The Futile Cycle?Plants (Basel, Switzerland) · 2021Review
- Metabolite Profiling and Network Analysis Reveal Coordinated Changes in Low-N Tolerant and Low-N Sensitive Maize Genotypes under Nitrogen Deficiency and Restoration Conditions.Plants (Basel, Switzerland) · 2020Article
- Cross-Species Comparison of Fruit-Metabolomics to Elucidate Metabolic Regulation of Fruit Polyphenolics Among Solanaceous Crops.Metabolites · 2020Article
- Liquid Chromatography-Mass Spectrometry Metabolic and Lipidomic Sample Preparation Workflow for Suspension-Cultured Mammalian Cells using Jurkat T lymphocyte Cells.Journal of proteomics & bioinformatics · 2015Article
- Crop improvement using life cycle datasets acquired under field conditions.Frontiers in plant science · 2015Review
- Flux profiling of photosynthetic carbon metabolism in intact plants.Nature protocols · 2014Article
- Systems Analysis of the Response of Photosynthesis, Metabolism, and Growth to an Increase in Irradiance in the Photosynthetic Model Organism Chlamydomonas reinhardtii.The Plant cell · 2014Article
- Article
- Utility of metabolomics toward assessing the metabolic basis of quality traits in apple fruit with an emphasis on antioxidants.Journal of agricultural and food chemistry · 2012Article
- Grand Challenges in Plant Systems Biology: Closing the Circle(s).Frontiers in plant science · 2012Article
- Analysis of constituents for phenotyping drought tolerance in crop improvement.Frontiers in physiology · 2012Article
- Tomato fruit photosynthesis is seemingly unimportant in primary metabolism and ripening but plays a considerable role in seed development.Plant physiology · 2011Article
- Transcriptional and metabolic programs following exposure of plants to UV-B irradiation.Plant signaling & behavior · 2011Review
- Recommendations for reporting metabolite data.The Plant cell · 2011Article
- Editorial overview - computational approaches in aid of advancing understanding in plant physiology.Frontiers in plant science · 2011Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although plant metabolomics is largely carried out on Arabidopsis it is essentially genome-independent, and thus potentially applicable to a wide range of species. However, transfer between species, or even between different tissues of the same species, is not facile. This is because the reliability of protocols for harvesting, handling and analysis depends on the biological features and chemical composition of the plant tissue. In parallel with the diversification of model species it is important to establish good handling and analytic practice, in order to augment computational comparisons between tissues and species. Liquid chromatography-mass spectrometry (LC-MS)-based metabolomics is one of the powerful approaches for metabolite profiling. By using a combination of different extraction methods, separation columns, and ion detection, a very wide range of metabolites can be analyzed. However, its application requires careful attention to exclude potential pitfalls, including artifactual changes in metabolite levels during sample preparation under variations of light or temperature and analytic errors due to ion suppression. Here we provide case studies with two different LC-MS-based metabolomics platforms and four species (Arabidopsis thaliana, Chlamydomonas reinhardtii, Solanum lycopersicum, and Oryza sativa) that illustrate how such dangers can be detected and circumvented.
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