Evidence map›Paper›PMID 22639110›Full record

ArticleChembiochem : a European journal of chemical biology2012

Bioconjugation of green fluorescent protein via an unexpectedly stable cyclic sulfonium intermediate.

Ramiz Nathani, Paul Moody, Mark E B Smith, Richard J Fitzmaurice, Stephen Caddick

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Derivatisable Cyanobactin Analogues: A Semisynthetic Approach.Chembiochem : a European journal of chemical biology · 2015
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ramiz NathaniDepartment of Chemistry, University College London, London, WC1H 0AJ, UK.
Paul Moody
Mark E B Smith
Richard J Fitzmaurice
Stephen Caddick

Funding

Wellcome TrustWellcome Trust 090145/Z/09/Z
6 · The paper itself

Abstract

Smooth converter: Bioconjugation of superfolder GFP involving the formation of an unusually stable, and unprecedented, cyclic sulfonium species is described. This sulfonium can undergo smooth reaction with a range of nucleophiles to give sulfur-, selenium- and azide-modified GFP derivatives in high conversions.

Indexed as

CysteineGreen Fluorescent ProteinsModels, MolecularMutationProtein ConformationSulfonium CompoundsCysteineGreen Fluorescent ProteinsSulfonium Compounds

Identifiers

PMID22639110
PMCPMC3487180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.