Evidence map›Paper›PMID 22639073›Full record

ArticleEuropean journal of nutrition2013

Breast milk fatty acid composition differs between overweight and normal weight women: the STEPS Study.

Johanna Mäkelä, Kaisa Linderborg, Harri Niinikoski, Baoru Yang, Hanna Lagström

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 5 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 5 syntheses or guidelines pooled it, 114 citations in OpenAlex.

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  5. The association between psychological factors and breastfeeding behaviour in women with a body mass index (BMI) ≥30 kg mObesity reviews : an official journal of the International Association for the Study of Obesity · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Johanna MäkeläTurku Institute for Child and Youth Research, University of Turku, Turku, Finland. jolepp@utu.fi
Kaisa Linderborg
Harri Niinikoski
Baoru Yang
Hanna Lagström
University of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe studied differences in breast milk fatty acid (FA) composition between overweight and normal weight women and the effect of FA composition on children's cholesterol concentrations at 13 months and growth from birth to 13 months.

methodsSamples were collected from lactating women (n = 100) participating in STEPS study at infant's age of 3 months, and FA composition was analyzed with gas chromatography. Diet of mother was studied with Index of Diet Quality at third trimester of pregnancy and with food frequency questionnaire on sampling day. The children's weights and heights were collected from hospital records at birth and during study visits at 13 months.

resultsOverweight women's breast milk compared to normal weight women's breast milk contained higher amount of saturated FAs (46.3 vs. 43.6 %, P = 0.012), lower amount of n-3FAs (2.2 vs. 2.7 %, P = 0.010), lower ratio of unsaturated to saturated FAs (1.1 vs. 1.3, P = 0.008), and higher ratio of n-6 to n-3 FAs (5.7 vs. 4.9, P = 0.031) than those of normal weight women even after adjusting for maternal diet (P < 0.05 for all). Normal weight women adhered more to dietary recommendations during pregnancy, whereas no differences were found in diet at sampling 3 months postpartum. The children's weight gains correlated with saturated FAs (R = 0.22, P = 0.04) and the ratio of unsaturated to saturated FAs (R = -0.23, P = 0.038) in milk; however, effects diminished after adjusting for total duration of breastfeeding. Milk FA composition was not associated with children's cholesterol concentrations at 13 months.

conclusionsBreast milk FA composition differed between overweight and normal weight women.

Indexed as

Body WeightMaternal Nutritional Physiological PhenomenaAdultCholesterolDietFatty AcidsFemaleHumansLactationLinear ModelsMilk, HumanOverweightPregnancySurveys and QuestionnairesCholesterolFatty Acids

Identifiers

PMID22639073
OpenAlexW2035401350

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.