ArticlePediatric cardiology2012
Functional expression and modulation of the L-type Ca2+ current in embryonic heart cells.
Article in Pediatric cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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0 citing papers in PubMed, 1 citations in OpenAlex.
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2 authors at 2 institutions in 1 country.
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Abstract
Voltage-dependent L-type Ca2+ channels (VDCCs) are critically involved in excitation contraction coupling and regulation of the force of contraction. An important mechanism contributing to the adaptation of heart function is modulation of the L-type Ca2+ current (I(Ca-L)) by hormones of the autonomous nervous system. The signaling pathways underlying this regulation in the adult heart are well understood. However, VDCC expression and its regulation in the embryonic heart are less understood. This report therefore provides a short overview of the current knowledge on this topic using embryonic stem cells and the mouse as model systems.
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