Evidence map›Paper›PMID 22635193›Full record

ArticleJournal of public health management and practice : JPHMP

Use of tuberculosis genotyping for postoutbreak monitoring.

Roque Miramontes, Carla A Winston, Maryam B Haddad, Patrick K Moonan

Abstract readComparative Study
In one paragraph

Article in Journal of public health management and practice : JPHMP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Tuberculosis Outbreaks in the United States, 2009-2015.Public health reports (Washington, D.C. : 1974)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Roque MiramontesDivision of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, GA, USA. rmiramontes@cdc.gov
Carla A Winston
Maryam B Haddad
Patrick K Moonan

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

contextReview of routinely collected tuberculosis genotyping results following a known outbreak is a potential mechanism to examine the effectiveness of outbreak control measures.

objectiveTo assess differences in characteristics between outbreak and postoutbreak tuberculosis cases.

designRetrospective.

settingUnited States.

participantsAll tuberculosis cases identified as a result of >5-person outbreaks investigated by the Centers for Disease Control and Prevention during 2003 to 2007 (original outbreak cases), and subsequent culture-positive tuberculosis cases with matching Mycobacterium tuberculosis genotypes reported in the same county during 2004 to 2008 (postoutbreak cases).

main outcome measureProportion of demographic, social, and clinical characteristics of tuberculosis outbreak cases compared to postoutbreak cases. SECONDARY: Proportion of demographic, social, and clinical characteristics of epidemiologically linked versus nonlinked cases.

resultsSix outbreaks with 111 outbreak cases and 110 postoutbreak cases were identified. Differences between outbreak and postoutbreak cases were gender (69% vs 85% male; P < .01), birth origin (3% vs 11% foreign-born; P = .02), disease severity (48% vs 62% sputum smear-positive; P = .04), homelessness (38% vs 51%; P = .05), and injection drug use (4% vs 11%; P = .04). For 5 of the 6 outbreaks, the status of epidemiologic relationships among postoutbreak cases was available (n = 89). The postoutbreak cases with a known epidemiologic link to the original outbreak were in younger persons (aged 39 vs 47 years; P < .01), and a larger proportion reported injection drug use (18% vs 4%; P = .04) or noninjection drug use (44% vs 18%; P < .01) than those without a reported link.

conclusionsHealth jurisdictions can utilize genotyping data to monitor and define the characteristics of postoutbreak cases related to the original outbreak.

Indexed as

Genotyping TechniquesAdolescentAdultAgedCenters for Disease Control and Prevention, U.S.ChildChild, PreschoolCulture TechniquesDisease OutbreaksEmigration and ImmigrationFemaleHumansIll-Housed PersonsInfantInfant, NewbornInfection Control

Identifiers

PMID22635193
PMCPMC4612591

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.