ArticleGene expression patterns : GEP
Cloning and expression analysis of Fgf5, 6 and 7 during early chick development.
Article in Gene expression patterns : GEP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Integrated Single-cell Analysis Uncovers Regulatory Logic of Cranial Ectoderm Development.bioRxiv : the preprint server for biology · 2025Article
- Comparative assessment of Fgf's diverse roles in inner ear development: A zebrafish perspective.Developmental dynamics : an official publication of the American Association of Anatomists · 2021Review
- Complex genetic architecture of three-dimensional craniofacial shape variation in domestic pigeons.Evolution & development · 2021Article
- Article
- Characterization and expression analysis of FGF6 (fibroblast growth factor 6) genes of grass carp (Ctenopharyngodon idellus) reveal their regulation on muscle growth.Fish physiology and biochemistry · 2019Article
- Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish.eLife · 2017Article
- Molecular mechanisms underlying the exceptional adaptations of batoid fins.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- FGFR1-Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation.PLoS genetics · 2014Article
- FGF5.Differentiation; research in biological diversityReview
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
FGFs with similar sequences can play different roles depending on the model organisms examined. Determining these roles requires knowledge of spatio-temporal Fgf gene expression patterns. In this study, we report the cloning of chick Fgf5, 6 and 7, and examine their gene expression patterns by whole mount in situ hybridization. We show that Fgf5's spatio-temporally restricted expression pattern indicates a potentially novel role during inner ear development. Fgf6 and Fgf7, although belonging to different subfamilies with diverged sequences, are expressed in similar patterns within the mesoderm. Alignment of protein sequences and phylogenetic analysis demonstrate that FGF5 and FGF6 are highly conserved between chick, human, mouse and zebrafish. FGF7 is similarly conserved except for the zebrafish, which has considerably diverged.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.