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ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2012

Chemotherapy-induced nausea and vomiting: pathophysiology and therapeutic principles.

Juan Bayo, Paula J Fonseca, Susana Hernando, S Servitja, A Calvo, S Falagan, Estefanía García, Iria González, María José de Miguel, Quionia Pérez and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Efficacy of steroid-omitting antiemetic therapy in patients with advanced pancreatic cancer receiving nano-liposomal irinotecan plus fluorouracil and leucovorin.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Central mechanisms of emesis: A role for GDF15.Neurogastroenterology and motility · 2025
    Review
  3. The antiemetic actions of GIP receptor agonism.American journal of physiology. Endocrinology and metabolism · 2024
    Review
  4. Review
  5. Review
  6. Article
  7. Guidelines versus individualized care for the management of CINV.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  8. CINV: still troubling patients after all these years.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  9. Article
  10. Therapeutic and preventive antiemetic effect of aprepitant in Japanese patients with thoracic malignancies who truly need it.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Juan BayoServicio de Oncología Médica, Hospital Juan Ramón Jiménez, C/ Ronda Norte, s/n, ES-21005 Huelva, Spain. juanbayo@yahoo.es
Paula J Fonseca
Susana Hernando
S Servitja
A Calvo
S Falagan
Estefanía García
Iria González
María José de Miguel
Quionia Pérez
Ana Milena
Antonio Ruiz
Agustí Barnadas

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemotherapy-induced nausea and vomiting (CINV) is a major determinant of quality of life in cancer patients. In addition, the perceptions that oncology professionals have about CINV quite often do not coincide with reality. Antineoplastic agents and their combinations can be categorised according to their emetogenic level, and this categorisation is helpful for classifying the severity of CINV and treating it. All CINV treatment guidelines emphasise the need to administer prophylaxis to patients who receive highly or moderately emetogenic chemotherapy. With the introduction of NK1 receptor antagonists, the control of acute and delayed CINV after highly or moderately emetogenic chemotherapy schedules has improved in the great majority of patients. NK1 receptor antagonists have been demonstrated to improve the control of CINV in all risk subgroups of patients.

Indexed as

AntiemeticsAntineoplastic AgentsHumansNauseaVomitingAntiemeticsAntineoplastic Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.