Evidence map›Paper›PMID 22634367›Full record

ReviewBrain, behavior, and immunity2013

Sleep disturbance, inflammation and depression risk in cancer survivors.

Michael R Irwin, Richard E Olmstead, Patricia A Ganz, Reina Haque

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Brain, behavior, and immunity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 4 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 4 syntheses or guidelines pooled it, 162 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. The biology of cancer-related fatigue: a review of the literature.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015
    Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Cognitive Behavioral Therapy for Insomnia Reduces Depression in Cancer Survivors.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Trial
  9. Trial
  10. Trial
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  12. Trial
  13. Trial
  14. Trial
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael R IrwinUniversity of California, Los Angeles - Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, CA 90095-7076, USA. mirwin1@ucla.edu
Richard E Olmstead
Patricia A Ganz
Reina Haque
University of California, Los Angeles · US

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
UCLA CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR033176 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2011 to 2011
$15.5M
UCLA OLDER AMERICANS INDEPENDENCE CENTERP30AG028748 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MOORE, ALISON AHERN · 2006 to 2017
$9.8M
Aging: Sleep and Inflammatory Mechanisms in Depression PreventionR01AG026364 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2005 to 2015
$5.8M
Sleep, Inflamation, and Depression Occurrence in Breast Cancer SurvivorsR01CA160245 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2012 to 2016
$3.9M
Chronic Moderate Sleep Restriction in Older Long and Older Average SleepersR01HL095799 · NHLBI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI IRWIN, MICHAEL R, JEAN-LOUIS, GIRARDIN · 2011 to 2015
$3.8M
Sleep and Immune Mechanisms in Rheumatoid ArthritisR01HL079955 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2006 to 2009
$3.0M
Cognitive Functioning After Breast Cancer TreatmentR01CA109650 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GANZ, PATRICIA A. · 2006 to 2010
$2.2M
Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune MechanismsR01CA119159 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2006 to 2010
$2.2M
Subjective Social Isolation and Sleep Disturbances: Inflammatory Mechanisms in AgR01AG034588 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2009 to 2013
$1.9M
ABC: Antidepressants and Breast Cancer PharmacoepidemiologyR01CA136743 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI HAQUE, REINA · 2010 to 2012
$1.7M
NCATS NIH HHS UL1 TR000124NCI NIH HHS R01 CA109650NCI NIH HHS R01-CA109650NCI NIH HHS R01 CA119159NCI NIH HHS R01-CA119159NCI NIH HHS R01 CA136743NCI NIH HHS R01CA136743-01A2NCI NIH HHS R01 CA160245NCRR NIH HHS UL1 RR033176NCRR NIH HHS UL RR 033176NHLBI NIH HHS R01 HL079955NHLBI NIH HHS R01-HL079955NHLBI NIH HHS R01 HL095799NIA NIH HHS P30 AG028748NIA NIH HHS P30-AG028748NIA NIH HHS R01 AG026364NIA NIH HHS R01-AG026364NIA NIH HHS R01 AG034588NIA NIH HHS R01-AG034588
6 · The paper itself

Abstract

Over two-thirds of the 11.4 million cancer survivors in the United States can expect long-term survival, with many others living with cancer as a chronic disease controlled by ongoing therapy. However, behavioral co-morbidities often arise during treatment and persist long-term to complicate survival and reduce quality of life. In this review, the inter-relationships between cancer, depression, and sleep disturbance are described, with a focus on the role of sleep disturbance as a risk factor for depression. Increasing evidence also links alterations in inflammatory biology dynamics to these long-term effects of cancer diagnosis and treatment, and the hypothesis that sleep disturbance drives inflammation, which together contribute to depression, is discussed. Better understanding of the associations between inflammation and behavioral co-morbidities has the potential to refine prediction of risk and development of strategies for the prevention and treatment of sleep disturbance and depression in cancer survivors.

Indexed as

DepressionDepressive DisorderHumansInflammationNeoplasmsQuality of LifeRiskSleep Wake DisordersSurvivors

Identifiers

PMID22634367
PMCPMC3435451
OpenAlexW2161967272

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.