ArticleJournal of cardiac failure2012
Prevalence, morbidity, and mortality of heart failure-related hospitalizations in children in the United States: a population-based study.
Article in Journal of cardiac failure, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 111 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dose Rationale for Dapagliflozin and Empagliflozin in Paediatric Heart Failure: a Phase II.a Pharmacokinetics, Ease-of-swallow, Safety and Proof-of-concept Study Among Children 6-18 Years of Age
Repurposing Empagliflozin for Duchenne Muscular Dystrophy - Associated Cardiomyopathy: a Pharmacokinetics, Safety and Proof-of-concept Study Among Children 6-18 Years of Age
Who cites it
111 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Technology landscape of pediatric mechanical circulatory support devices: A systematic review 2010-2021.Artificial organs · 2022Pooled it
- Complications in children with ventricular assist devices: systematic review and meta-analyses.Heart failure reviews · 2022Pooled it
- An Adult Population Pharmacokinetic Model to Simulate Subcutaneous Administration of a Fixed Dose of Furosemide in Adolescents with Heart Failure and Volume Overload.Clinical pharmacokinetics · 2025Trial
- Tamoxifen may contribute to preserve cardiac function in Duchenne muscular dystrophy.European journal of pediatrics · 2024Trial
- Baseline Characteristics of Pediatric Patients With Heart Failure Due to Systemic Left Ventricular Systolic Dysfunction in the PANORAMA-HF Trial.Circulation. Heart failure · 2023Trial
- Repurposing Empagliflozin for Duchenne Muscular Dystrophy-Associated Cardiomyopathy: Protocol for a Pharmacokinetics, Safety and Proof-of-Concept Trial in Children.Cardiology and therapy · 2026Article
- Beyond Survival: Child and Parent Well-Being in Pediatric Heart Failure.Pediatric cardiology · 2026Article
- Pediatric Versus Adult Shear-Induced Hemolysis: Are Age-Related Blood Properties the Main Cause for Differences?Artificial organs · 2026Article
- An Integrated Heart Sound-Electrocardiogram Synchronization System for Early Detecting Left Ventricular Systolic Dysfunction in Pediatric Populations.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Article
- Use of the AM-PAC 6 Clicks Basic Mobility Short Forms as a Measure of Functional Change in the Pediatric Heart Failure Population.Archives of rehabilitation research and clinical translation · 2026Article
- Pediatric heart failure in the era of cardio-immunology: inflammatory-immune context phenotypes, diagnosis, and targeted management.Frontiers in immunology · 2026Review
- An overview of the benefits of animal-assisted interventions in medical and therapeutic contexts for human health: cognitive mechanisms, sensory perception and welfare considerations.Frontiers in veterinary science · 2026Review
- Berlin Heart EXCOR as a Bridge to Transplantation in Pediatric End-Stage Heart Failure: A Retrospective Cohort Study.Journal of cardiovascular development and disease · 2025Article
- Pediatric Heart Failure Pharmacotherapy: Transformative Insights for the Future.Reviews in cardiovascular medicine · 2025Review
- LVEF 53% as a Novel Mortality Predictor in Pediatric Heart Failure: A Multicenter Biomarker-Stratified Analysis.Diagnostics (Basel, Switzerland) · 2025Article
- Innovative strategies to increase cardiac donor availability.World journal of transplantation · 2025Review
- Review
- Capturing Physiological Data in Children With Heart Failure Using Wearable Digital Technology: Lessons From Pilot Project.CJC pediatric and congenital heart disease · 2025Article
- End-stage paediatric heart failure in low- and middle-income countries: challenges in surgical management.Indian journal of thoracic and cardiovascular surgery · 2025Article
- Cardiac magnetic resonance and genetics in pediatric heart failure patients with nonischemia: prognostic implications.World journal of pediatrics : WJP · 2025Article
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew data exist on prevalence, morbidity, and mortality of pediatric heart failure hospitalizations. We tested the hypotheses that pediatric heart failure-related hospitalizations increased over time but that mortality decreased. Factors associated with mortality and length of stay were also assessed. METHODS AND
resultsA retrospective analysis of the Healthcare Cost and Utilization Project Kids' Inpatient Database was performed for pediatric (age ≤18 years) heart failure-related hospitalizations for the years 1997, 2000, 2003, and 2006. Hospitalizations did not significantly increase over time, ranging from 11,153 (95% confidence interval [CI] 8,898-13,409) in 2003 to 13,892 (95% CI 11,528-16,256) in 2006. Hospital length of stay increased from 1997 (mean 13.8 days, 95% CI 12.5-15.2) to 2006 (mean 19.4 days, 95% CI 18.2 to 20.6). Hospital mortality was 7.3% (95% CI 6.9-8.0) and did not vary significantly between years; however, risk-adjusted mortality was less in 2006 (odds ratio 0.70, 95% CI 0.61 to 0.80). The greatest risk of mortality occurred with extracorporeal membrane oxygenation, acute renal failure, and sepsis.
conclusionsHeart failure-related hospitalizations occur in 11,000-14,000 children annually in the United States, with an overall mortality of 7%. Many comorbid conditions influenced hospital mortality.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.