Evidence map›Paper›PMID 22633067›Full record

ReviewCurrent opinion in chemical biology2012

DNA synthesis, assembly and applications in synthetic biology.

Siying Ma, Nicholas Tang, Jingdong Tian

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 110 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Codon-optimization in gene therapy: promises, prospects and challenges.Frontiers in bioengineering and biotechnology · 2024
    Review
  10. Review
  11. Review
  12. Automating Glycan Assembly in Solution.ACS central science · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Large-ScaleFrontiers in bioengineering and biotechnology · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Siying MaDepartment of Biomedical Engineering and the Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA.
Nicholas Tang
Jingdong Tian
Duke University · US

Funding

Automated long DNA synthesis technologyR01HG005862 · NHGRI · DUKE UNIVERSITY · PI TIAN, JINGDONG · 2011 to 2014
$1.5M
NHGRI NIH HHS R01 HG005862NHGRI NIH HHS R01HG005862
6 · The paper itself

Abstract

The past couple of years saw exciting new developments in microchip-based gene synthesis technologies. Such technologies hold the potential for significantly increasing the throughput and decreasing the cost of gene synthesis. Together with more efficient enzymatic error correction and genome assembly methods, these new technologies are pushing the field of synthetic biology to a higher level.

Indexed as

DNAGenomeSynthetic BiologyDNA

Identifiers

PMID22633067
PMCPMC3424320
OpenAlexW2028367976

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.