Evidence map›Paper›PMID 22632702›Full record

ReviewPM & R : the journal of injury, function, and rehabilitation2012

Resistance exercise for knee osteoarthritis.

Kevin R Vincent, Heather K Vincent

4 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in PM & R : the journal of injury, function, and rehabilitation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02730598 nacompletednot on this mapstarted 2016, after this paper: background citation

Determining Efficacy of the Combined Application of Electrical Stimulated Antagonist Contraction During Walking With Sensory TENS for Increasing Strength and Decreasing Pain in Women With Frequent Knee Symptoms

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2016 to 2017Enrolled28ConditionsKnee OsteoarthritisArmsHybrid Training System (HTS), Sensory TENS
NCT02802878 nacompletednot on this mapstarted 2016, after this paper: background citation

Determining the Effects of the Combined Application of Electrical Stimulation and Volitional Contractions on Muscle Strength and Knee Pain and Function in Women With or at Risk for Knee Osteoarthritis

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2016 to 2016Enrolled42ConditionsKnee OsteoarthritisArmsHybrid Training using Electrodes and Joint Motion Sensors, Isokinetic Training with Isokinetic Dynamometer
NCT04187092 nacompletednot on this mapstarted 2020, after this paper: background citation

Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy ("KneeBRIGHT") Phase II

TypeinterventionalSponsorUniversity of VirginiaRan2020 to 2021Enrolled38ConditionsOsteo Arthritis KneeArmsKneeBright Group, Standard Rehabilitation group
NCT06875817 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Feldenkrais Exercises on Pain, Range of Motion, and Disability in Patients With Knee Osteoarthritis

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2025Enrolled32ConditionsKnee Osteoarthritis (Knee OA)ArmsFeldenkrais exercises, Standard physical therapy interventions
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it, 170 citations in OpenAlex.

  1. Pooled it
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  15. Exercise approaches in obese individuals with physical limitations.Turkish journal of physical medicine and rehabilitation · 2026
    Review
  16. Review
  17. Hemochromatosis osteoarthritis.Frontiers in endocrinology · 2026
    Review
  18. Review
  19. Article
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kevin R VincentDepartment of Orthopaedics and Rehabilitation, Divisions of Sports Medicine, Physical Medicine and Research, UF Orthopaedics and Sports Medicine Institute, PO Box 112727, University of Florida, Gainesville, FL 32611, USA. vincekr@ortho.ufl.edu
Heather K Vincent
University of Florida · US

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Marco Pahor · 2007 to 2026
$22.8M
Comparative Resistance Exercise Effects on Knee Osteoarthritis Pain, Functional IK23AR061146 · NIAMS · UNIVERSITY OF FLORIDA · PI VINCENT, KEVIN ROBERT · 2012 to 2014
$375k
Comparative Resistance Exercise Effects on Knee Osteoarthritis Pain, Functional IR03AR059786 · NIAMS · UNIVERSITY OF FLORIDA · PI VINCENT, KEVIN ROBERT · 2010 to 2012
$214k
Resistance Exercise Effects on Fear Avoidance Beliefs and Physical Function in ObR03AR057552 · NIAMS · UNIVERSITY OF FLORIDA · PI VINCENT, HEATHER KETELAAR · 2010 to 2012
$203k
NIAMS NIH HHS #AR057552-01A1NIAMS NIH HHS #AR059786NIAMS NIH HHS K23 AR061146NIAMS NIH HHS R03 AR057552NIAMS NIH HHS R03 AR059786NIA NIH HHS P30 AG028740
6 · The paper itself

Abstract

The initiation, progression, and severity of knee osteoarthritis (OA) have been associated with decreased muscular strength and alterations in joint biomechanics. Chronic OA pain may lead to anxiety, depression, fear of movement, and poor psychological outlook. The fear of movement may prevent participation in exercise and social events, which could lead to further physical and social isolation. Resistance exercise (RX) has been shown to be an effective intervention both for decreasing pain and improving physical function and self-efficacy. RX may restore muscle strength and joint mechanics while improving physical function. RX also may normalize muscle firing patterns and joint biomechanics, leading to reductions in joint pain and cartilage degradation. These physical adaptations could lead to improved self-efficacy and decreased anxiety and depression. RX can be prescribed and performed by patients across the spectrum of OA severity. When designing and implementing an RX program for a patient with knee OA, one should consider both the degree of OA severity and the level of pain. RX, either in the home or at a fitness facility, is an important component of a comprehensive regimen designed to offset the physical and psychological limitations associated with knee OA. Unique considerations for this population include (1) monitoring pain during and after exercise, (2) providing days of rest when disease flares occur, and (3) infusing variety into the exercise regimen to encourage adherence.

Indexed as

Resistance TrainingGuidelines as TopicHumansKnee JointMuscle, SkeletalMuscle StrengthOsteoarthritis, KneePatient ComplianceRandomized Controlled Trials as TopicRehabilitation

Identifiers

PMID22632702
PMCPMC3635671
OpenAlexW2034730935

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.