ReviewPM & R : the journal of injury, function, and rehabilitation2012
Aerobic activity in prevention and symptom control of osteoarthritis.
Review in PM & R : the journal of injury, function, and rehabilitation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Effects of three types of resistance training on knee osteoarthritis: A systematic review and network meta-analysis.PloS one · 2024Pooled it
- A systematic review of studies using pedometers as an intervention for musculoskeletal diseases.BMC musculoskeletal disorders · 2014Pooled it
- The cost-effectiveness of an online intervention to prevent dementia: Results from the Maintain Your Brain (MYB) randomised controlled trial.The journal of prevention of Alzheimer's disease · 2025Trial
- Randomized blinded trial of standardized written patient information before total knee arthroplasty.PloS one · 2017Trial
- Kaatsu training to enhance physical function of older adults with knee osteoarthritis: Design of a randomized controlled trial.Contemporary clinical trials · 2015Trial
- Physical Function and Pain as Predictors of Movement Behaviors in Adults With Arthritis.American journal of health promotion : AJHP · 2026Article
- A Catalog of "Knee Friendly" Aerobic Exercises Developed for Patients With Knee Osteoarthritis: An International Patient Survey.ACR open rheumatology · 2025Article
- Effect of Moderate Exercise on the Superficial Zone of Articular Cartilage in Age-Related Osteoarthritis.Diagnostics (Basel, Switzerland) · 2023Article
- Review
- Article
- Blood-Flow Restriction Resistance Exercise for Older Adults with Knee Osteoarthritis: A Pilot Randomized Clinical Trial.Journal of clinical medicine · 2019Article
- Effect of a Moderate-Intensity Aerobic Training on Joint Biomarkers and Functional Adaptations in Rats Subjected to Induced Knee Osteoarthritis.Frontiers in physiology · 2019Article
- What are the perceptions about running and knee joint health among the public and healthcare practitioners in Canada?PloS one · 2018Article
- Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats.Arthritis & rheumatology (Hoboken, N.J.) · 2017Article
- Pain rather than self-reported sedentary time explains variation in perceived health and activity limitation in persons with rheumatoid arthritis: a cross sectional study in Sweden.Rheumatology international · 2017Article
- Running decreases knee intra-articular cytokine and cartilage oligomeric matrix concentrations: a pilot study.European journal of applied physiology · 2016Article
- Objectively Measured Physical Activity and Symptoms Change in Knee Osteoarthritis.The American journal of medicine · 2016Article
- Construction workers working in musculoskeletal pain and engaging in leisure-time physical activity: Findings from a mixed-methods pilot study.American journal of industrial medicine · 2014Article
- Neuromuscular function in painful knee osteoarthritis.Current pain and headache reports · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Almost 27 million adults in the United States experience some form of osteoarthritis (OA). An epidemic of arthritis-associated disability is expected in the United States during the next 2 decades, largely fueled by the aging population and the tremendous growth in the prevalence of knee OA. Regular physical activity (PA), particularly strengthening and aerobic activity, can reduce pain and improve function and health status among patients with knee and hip OA. The focus of this review is on the impact of aerobic activity on the progression and symptom control of OA. In general, both strengthening and aerobic exercise are associated with improvements in pain, perceived physical function, and performance measures for persons with lower limb OA, although comparisons of strengthening versus aerobic exercise on these outcomes are unusual. Structural disease progression in persons with established OA has been directly evaluated by a limited number of PA clinical trials for persons with knee OA, but these protocols focused on strength training exclusively. In healthy subjects, it appears that overall PA is beneficial, rather than detrimental, to knee joint health. Possibly the most important reason for engaging in PA is to prevent obesity, which independently has been associated with many serious chronic diseases, including the incidence and progression of OA. More research is needed to determine the optimal types and dosing of aerobic conditioning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.