ArticleSurgical neurology international2012
Primary spinal extradural Ewing's sarcoma (primitive neuroectodermal tumor): Report of a case and meta-analysis of the reported cases in the literature.
Article in Surgical neurology international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 62 citations in OpenAlex.
- Decoding pediatric spinal tumors: a single-center retrospective case series on etiology, presentation, therapeutic strategies, and outcomes.Neurosurgical review · 2024Article
- Advances in the multidisciplinary surgical approach to primary spinal sarcomas: insights from a retrospective case series on outcomes and survival.Acta neurochirurgica · 2024Article
- Extraskeletal Ewing sarcoma of the sciatic nerve.Radiology case reports · 2023Article
- Single-cell transcriptional profiling reveals heterogeneity and developmental trajectories of Ewing sarcoma.Journal of cancer research and clinical oncology · 2022Article
- Primary intradural extramedullary Ewing sarcoma in the lumbar area: A case report.Radiology case reports · 2022Article
- Metastatic thoracic and lumbar intramedullary and extramedullary Ewing's sarcoma: a rare case report and literature review.The Journal of international medical research · 2022Review
- Prognosis and Outcome of Cervical Primary Extraosseous Intradural Extramedullary Ewing Sarcoma: A Systematic Review.Cureus · 2022Review
- The Role of Neuroaxis Irradiation in the Treatment of Intraspinal Ewing Sarcoma: A Review and Meta-Analysis.Cancers · 2022Review
- A case of giant Ewing's sarcoma (EES)/primitive neuroectodermal tumor (PNET) of the cervicothoracic junction in children with incomplete paralysis of both lower limbs: Case report and literature review.Frontiers in surgery · 2022Article
- Primitive neuroectodermal tumor of the pericardium: a case report and literature review.BMC cardiovascular disorders · 2021Review
- Outcome of multidisciplinary treatment of peripheral primitive neuroectodermal tumor.Scientific reports · 2020Article
- Primary Ewing's sarcoma of the petroclival bone: A case report and literature review.Surgical neurology international · 2020Article
- Primary Spinal Epidural/Extramedullary Ewing Sarcoma in Young Female Patients.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2019Article
- Treatment Outcomes and Prognostic Factors of Patients With Primary Spinal Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumors.Frontiers in oncology · 2019Article
- Cervicomedullary primitive neuroectodermal tumor of the spine: Case report.Surgical neurology international · 2018Article
- Primary pericardial primitive neuroectodermal tumor: a case report and review of literature.International journal of clinical and experimental pathology · 2018Article
- Peripheral primitive neuroectodermal tumors of the spine: a case report and review of the literature.BMC research notes · 2016Review
- Adult Primary Spinal Epidural Extraosseous Ewing's Sarcoma: A Case Report and Review of the Literature.Case reports in neurological medicine · 2016Article
- Clinical presentation and long-term outcome of primary spinal peripheral primitive neuroectodermal tumors.Journal of neuro-oncology · 2015Article
- Peripheral primitive neuroectodermal tumor of the dura in a 51-year-old woman following intensive treatment for breast cancer.The American journal of case reports · 2014Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary spinal primitive neuroectodermal tumors (PNET) and/or spinal extraskeletal Ewing's sarcoma family tumors (ESET) are rare lesions appearing in the spinal extradural space. One hundred forty-one primary spinal PNETs, including 29 intramedullary lesions, have been reported in the literature. Encountering a case of primary epidural EES/peripheral PNET (pPNET) in sacral level, which is the fifth one occurring at this level in the literature, we have tried to conduct a meta-analysis of the reported cases. CASE DESCRIPTION: A 44-year-old lady with epidural EES/pPNET is reported here. She was once operated for L5/S1 herniated disc, which did not ameliorate her symptoms. The clinical, imaging, surgical, and histopathologic characteristics of our case are presented and wide search of the literature is also done. All the reports were level 3 or less evidences and most of the series had missing parts. 106 cases of primary intraspinal (extradural/extramedullary-intradural) EES/pPNET and 29 cases of primary intramedullary PNET (CNS-PNET) have been reported in the literature. The most common clinical presentation in both entities was muscle weakness proportionate to the tumor location. Distant metastasis occurred in 38 of 99 (38%) cases of primary intraspinal EES/pPNET, while the rate of metastasis was 48% in patients with PNETs occurring in the intramedullary region (P > 0.05). One-year survival rate of the patients who underwent chemo-radiation after total or subtotal resection was better than those who did not receive chemotherapy or radiotherapy, or did not have total or subtotal resection. However, this difference was not repeated in 2-year survival rate in any of the tumor groups.
conclusionIt seems that total or subtotal removal of the tumor and adjuvant chemo- and radiation therapy can improve the outcome in these patients.
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