Trial reportPloS one2012
Measurement of ad libitum food intake, physical activity, and sedentary time in response to overfeeding.
Trial report in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00342732 (The Food Intake Phenotype), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Food Intake Phenotype: Assessing Eating Behavior and Food Preferences as Risk Factors for Obesity
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Physical activity, energy expenditure and sedentary parameters in overfeeding studies - a systematic review.BMC public health · 2018Pooled it
- Short-term overeating results in incomplete energy intake compensation regardless of energy density or macronutrient composition.Obesity (Silver Spring, Md.) · 2014Trial
- Dietary magnesium intakes among women of reproductive age in Ghana-A comparison of two dietary analysis programs.PloS one · 2023Article
- Effect of 8 weeks of supervised overfeeding on eating attitudes and behaviors, eating disorder symptoms, and body image: Results from the PROOF and EAT studies.Eating behaviors · 2021Article
- The unidentified hormonal defense against weight gain.PLoS biology · 2020Article
- Fasting glucagon-like peptide 1 concentration is associated with lower carbohydrate intake and increases with overeating.Journal of endocrinological investigation · 2019Article
- Free-Living Responses in Energy Balance to Short-Term Overfeeding in Adults Differing in Propensity for Obesity.Obesity (Silver Spring, Md.) · 2018Article
- A Human Thrifty Phenotype Associated With Less Weight Loss During Caloric Restriction.Diabetes · 2015Article
- Measurement of body composition in response to a short period of overfeeding.Journal of physiological anthropology · 2014Article
- Circulating glucagon-like peptide-1 increases in response to short-term overfeeding in men.Nutrition & metabolism · 2013Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
unlabelledGiven the wide availability of highly palatable foods, overeating is common. Energy intake and metabolic responses to overfeeding may provide insights into weight gain prevention. We hypothesized a down-regulation in subsequent food intake and sedentary time, and up-regulation in non-exercise activity and core temperature in response to overfeeding in order to maintain body weight constant. In a monitored inpatient clinical research unit using a cross over study design, we investigated ad libitum energy intake (EI, using automated vending machines), core body temperature, and physical activity (using accelerometry) following a short term (3-day) weight maintaining (WM) vs overfeeding (OF) diet in healthy volunteers (n = 21, BMI, mean ± SD, 33.2±8.6 kg/m(2), 73.6% male). During the ad libitum periods following the WM vs. OF diets, there was no significant difference in mean 3-d EI (4061±1084 vs. 3926±1284 kcal/day, p = 0.41), and there were also no differences either in core body temperature (37.0±0.2°C vs. 37.1±0.2°C, p = 0.75) or sedentary time (70.9±12.9 vs. 72.0±7.4%, p = 0.88). However, during OF (but not WM), sedentary time was positively associated with weight gain (r = 0.49, p = 0.05, adjusted for age, sex, and initial weight). In conclusion, short term overfeeding did not result in a decrease in subsequent ad libitum food intake or overall change in sedentary time although in secondary analysis sedentary time was associated with weight gain during OF. Beyond possible changes in sedentary time, there is minimal attempt to restore energy balance during or following short term overfeeding.
trial registrationClinicalTrials.gov NCT00342732.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.