Evidence map›Paper›PMID 22629287›Full record

ArticleThe open neurology journal2012

Medical marijuana: clearing away the smoke.

Igor Grant, J Hampton Atkinson, Ben Gouaux, Barth Wilsey

Registry-linked trialAbstract read
In one paragraph

Article in The open neurology journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02460692 (A Randomized Controlled Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02460692 phase2completednot on this mapstarted 2016, after this paper: background citation

A Randomized Controlled Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain

TypeinterventionalSponsorUniversity of California, San DiegoRan2016 to 2020Enrolled131ConditionsCannabis, Low Back Pain, Neuropathic PainArmsPlacebos, dronabinol, Vaporized Cannabis 3.7% THC/5.6% CBD
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Cannabinoids in Gynecological Diseases.Medical cannabis and cannabinoids · 2019
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Protective Behavioral Strategies for Marijuana Scale: Further examination using item response theory.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017
    Article
  15. The Use of Cannabis for Headache Disorders.Cannabis and cannabinoid research · 2017
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Igor GrantCenter for Medicinal Cannabis Research; University of California, San Diego; San Diego, CA, USA.
J Hampton Atkinson
Ben Gouaux
Barth Wilsey

Funding

The Effect of Vaporized Cannabis on Neuropathic Pain in Spinal Cord InjuryR01DA030424 · NIDA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ZHAO, HOLLY · 2011 to 2014
$895k
NIDA NIH HHS R01 DA030424
6 · The paper itself

Abstract

Recent advances in understanding of the mode of action of tetrahydrocannabinol and related cannabinoid in-gredients of marijuana, plus the accumulating anecdotal reports on potential medical benefits have spurred increasing re-search into possible medicinal uses of cannabis. Recent clinical trials with smoked and vaporized marijuana, as well as other botanical extracts indicate the likelihood that the cannabinoids can be useful in the management of neuropathic pain, spasticity due to multiple sclerosis, and possibly other indications. As with all medications, benefits and risks need to be weighed in recommending cannabis to patients. We present an algorithm that may be useful to physicians in determining whether cannabis might be recommended as a treatment in jurisdictions where such use is permitted.

Indexed as

Cannabischronic painpain.

Identifiers

PMID22629287
PMCPMC3358713

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.